Houston Astros vs Seattle Mariners Prediction 4/8/25 MLB Picks

Seattle Mariners (4-7) vs Houston Astros (4-6)

Game Info: Tuesday, April 8, 2025 at 9:40 pm (T-Mobile Park)

F. Valdez (L) vs L. Castillo (R)

Betting Odds: Seattle Mariners -105 / Houston Astros -115 --- Over/Under: 7 Click Here for the Latest Odds

Where to Watch: MLB.TV

The Houston Astros and the Seattle Mariners meet on Tuesday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Houston Astros did not have a starting pitcher announced at the time that this article was posted. The Seattle Mariners will send out Luis Castillo for the start here, and Castillo is 1-1 with a 3.00 ERA and 9 strikeouts so far this season. In his last five starts against the Astros, Castillo is 1-2 with a 3.82 ERA and 25 strikeouts.

Houston Astros Recap

The Houston Astros will be out to bounce back from a 4-3 loss at the hands of the Mariners on Monday to fall to 4-6 on the year. After this series, the Astros will return to Houston for a series with the Los Angeles Angels.

Astros Looking For Some Consistency

Jose Altuve leads the Astros with 12 hits, including a pair of solo home runs, while also boasting a team-high 11 strikeouts. Jeremy Pena also has a pair of solo homers and a pair of stolen bases, while Yordan Alvarez has a double and a team-high 4 RBIs with 11 strikeouts as well. Brendan Rodgers has a pair of doubles and 3 RBIs, and Christian Walker has also accrued 11 strikeouts so far this season.

Why the Houston Astros will win

  • The Mariners have lost each of their last nine Tuesday games.
  • The Astros have won each of their last four road games following a loss.
  • The Astros have covered the run line in each of their last nine road games against American League opponents following a loss.
  • The Mariners have failed to cover the run line each of their last nine Tuesday games against teams that held a losing record.

Houston Astros Player Prop Facts

  • Yordan Alvarez has recorded a Double in three of his last four appearances with the Astros as favorites against AL opponents.
  • Jose Altuve has recorded at least one RBI in five of the Astros' last six games against AL opponents that held a losing record.
  • Yordan Alvarez has hit a home run in four of the Astros' last five games as road favorites against AL West opponents.
  • Jose Altuve has scored at least one run in six of the Astros' last seven games.
  • Framber Valdez has recorded a win in six of his last seven appearances in night games.
  • Brendan Rodgers has recorded at least one Single in seven of his last eight road appearances against opponents that held a losing record.
  • Framber Valdez has recorded six or more strikeouts in four of his last five road appearances.
  • Jose Altuve has recorded at least one hit in each of his last 13 road appearances against the Mariners after playing the previous day.
  • Jose Altuve ranks T5th in the league in Hits (15) this season.

Seattle Mariners Recap

The Seattle Mariners will be looking to keep the ball rolling after their series-opening win over the Astros to improve to 4-7 on the year. After this series, the Mariners will welcome the Texas Rangers to town for another divisional set.

Mariners Snap Three-Game Losing Streak

Jorge Polanco has 9 hits, including a pair of home runs and 8 RBIs, while Victor Robles has a team-high 12 hits with a team-high 3 doubles. Randy Arozarena has 5 hits with 3 doubles and a pair of home runs but also leads Seattle with 14 strikeouts as well on the year. Julio Rodriguez has chipped in 8 hits with 3 home runs and a triple and a team-high 3 stolen bases, while Robles also has 3 SB, and Cal Raleigh and Ryan Bliss have each added a pair of stolen bags as well on the year.

Why the Seattle Mariners will win

  • The Mariners have won seven of their last eight games as underdogs against AL West opponents.
  • The Astros have lost four of their last five games as favorites against American League opponents.
  • The Mariners have covered the run line in each of their last eight games as underdogs against AL West opponents.
  • The Astros have failed to cover the run line in each of their last seven games as favorites after playing the previous day.

Seattle Mariners Player Prop Facts

  • Jorge Polanco has hit a home run in each of his last two appearances with the Mariners as underdogs.
  • Randy Arozarena has recorded a Double in each of the Mariners' last three games as underdogs against AL opponents.
  • Jorge Polanco has recorded at least one RBI in each of his last four appearances.
  • Julio Rodriguez has scored at least one run in each of the Mariners' last four games as underdogs against AL West opponents.
  • Jorge Polanco has recorded at least one Single in each of his last seven appearances in night games against teams that held a losing record.
  • Luis Castillo has recorded seven or more strikeouts in each of his last six Tuesday appearances with his team as an underdog.
  • Jorge Polanco has recorded at least one hit in each of his last 10 appearances in night games.

Total Runs Facts

  • Four of the Astros' last five night games after playing the previous day have gone UNDER the total runs line.
  • Nine of the last 12 games between the Astros and Mariners at T-Mobile Park have gone UNDER the total runs line.

Houston Astros vs. Seattle Mariners Prediction

I’m on the under in this game. Despite the Mariners picking up the win on Monday, I’m still not trusting the Mariners to do very much at the plate, as this offense is still wildly inconsistent. On the other side, the one thing that Houston’s offense has done consistently is struggle, as Houston’s scored 3 runs or less in 8 of their 10 games so far this season, and Castillo is still one of the better starting options that this Mariner rotation has to offer. All in all I’m expecting another low-scoring battle, so give me the under in this one.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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