Los Angeles Angels vs St. Louis Cardinals Prediction 4/2/25 MLB Picks

St. Louis Cardinals (3-2) vs Los Angeles Angels (4-1)

Game Info: Wednesday, April 2, 2025 at 1:15 pm (Busch Stadium)

Y. Kikuchi (L) vs S. Gray (R)

Betting Odds: St. Louis Cardinals -155 / Los Angeles Angels +130 --- Over/Under: 8.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

In this article, we will formulate a Los Angeles Angels vs St. Louis Cardinals Prediction for this MLB game on Wednesday, April 3rd, at Busch Stadium. To formulate this prediction, we will look at: 

-The Angels’ recent form and recent player performance 

-The Cardinals’ recent form and recent player performance

-Recent Betting trends and streaks involving Los Angeles

-Recent Betting trends and streaks involving St. Louis

-Recent betting trends in games played between Los Angeles and St. Louis

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Angels and Cardinals. 

What a Start for the Angels

It has been quite the start for the Angels to the season, and they have lost only one game so far this season. On Tuesday, it took extra innings, and they tried to find a way to blow it, but they ended up picking up the 9-7 win. Mike Trout has gotten out to a slow start to the season, but maybe Tuesday was all he needed. He finished the game with one hit and two RBIs. Kyle Hendricks got the start, and he played with a little bit of fire, but they still ended up working out of trouble and giving up two earned runs in six innings. 

Yusei Kikuchi is going to get the start for the Angels, and he was the big offseason addition for this team. Coming into this one, he sits with a 0-1 record and an ERA of 4.50. Against the Chicago White Sox in the first game, he went six innings, giving up five hits and three runs. 

Why the Angels Will Beat the Cardinals

  • The underdogs have won eight of the Cardinals' last nine games.
  • The Cardinals have lost each of their last five games as home favorites after going to extra innings.
  • The underdogs have covered the run line in each of the Cardinals' last nine games at Busch Stadium.
  • The Cardinals have failed to cover the run line in 13 of their last 14 games as favorites following a loss.
  • The Cardinals have trailed after 3 innings in three of their last four day games against opponents that held a winning record.

Cardinals Need Better Pitching

The Cardinals need better pitching, especially late in the game. They gave up three runs in the 10th and 11th innings each, leading to the defeat. Ryan Fernandez went an inning, giving up two hits and two runs. Chris Roycroft went one inning, giving up two hits and two runs. The Cardinals used four bullpen guys, and they will be a little shorthanded out there for this game. Jordan Walker did hit a home run and drove in two RBIs. Lars Nootbaar has been the top player according to the stats, hitting two home runs and driving in five RBIs. 

Sonny Gray gets the start for the Cardinals, and he led the squad to an opening day win. Against the Minnesota Twins, he went 5.0 innings, giving up four hits and two runs. He had six strikeouts and two walks. The Cards will meet the Red Sox after this series.

Total Runs Facts

  • Each of the Cardinals' last six games as favorites against AL West opponents have gone OVER the total runs line.
  • Seven of the Angels' last eight games as road underdogs have gone OVER the total runs line.
  • The 'Inning 1 UNDER 0.5 runs' market has hit in each of the Cardinals' last seven Wednesday day games against American League opponents.
  • The 'Inning 1 OVER 0.5 runs' market has hit in each of the Angels' last six Wednesday games against National League opponents.

Los Angeles Angels vs St. Louis Cardinals Prediction

This is a great bounce-back spot for Kikuchi. He really did deal with some bad luck in his first start, but he’s going to be better here. Sonny Gray has been solid, but the Angels' offense can’t be overlooked. It’s been impressive that they have been able to win the games, even with Trout’s bat being mostly cold. At worst, this game should be a pick-em. Give me the value here with the Angels on the money line. 

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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