Boston Red Sox vs Baltimore Orioles Prediction 4/2/25 MLB Picks

Baltimore Orioles Betting Preview

The Baltimore Orioles are 3-2 on the year and play the Royals, Diamondbacks, and Blue Jays next. The Baltimore Orioles are batting .305 on the season, have a .364 OBP, and a .517 slugging percentage. The Baltimore Orioles pitching staff has a 4.60 ERA and a 1.40 WHIP. Tyler O’Neill leads the Baltimore Orioles with 8 hits and 5 RBI, while Jordan Westburg and Cedric Mullins have combined for 14 hits and 13 RBI.

Zach Eflin gets the ball for the Baltimore Orioles, and he is 1-0 with a 3.00 ERA and 2 strikeouts this season. Eflin is 3-0 with a 5.10 ERA and 35 strikeouts in his career against the Boston Red Sox.

Why the Baltimore Orioles will win

• The Red Sox have lost eight of their last nine road games against teams that held a winning record.
• The Orioles have won three of their last four games as home underdogs against American League opponents.
• The Red Sox have failed to cover the run line in four of their last five games against AL East opponents.
• The Orioles have covered the run line in four of their last five games as underdogs against the Red Sox following a home win.
• The Orioles have led after 5 innings in three of their last four night games at Oriole Park at Camden Yards against American League opponents.
• The Red Sox have trailed after 3 innings in each of their last four games.

Why the Boston Red Sox will win

• The Red Sox have won each of their last five night games at Oriole Park at Camden Yards following a road loss.
• The Orioles have lost four of their last five games at Oriole Park at Camden Yards.
• The Red Sox have covered the run line in 13 of their last 14 night games against the Orioles at Oriole Park at Camden Yards following a road loss.
• The Orioles have failed to cover the run line in four of their last five games as underdogs against AL East opponents following a win.
• The Red Sox have led after 5 innings in three of their last four games against American League opponents that held a winning record.

Boston Red Sox vs Baltimore Orioles Prediction

This should be a fun matchup between two above-average pitchers in Crochet and Eflin, and you can make a case for either side. I’m siding with the Orioles and the even money, as the O’s have been better offensively through five games, and that includes scoring eight or more runs in three of those contests. The Red Sox will get their act together at some point, but these last four games have been a tough watch. Rafael Devers is key to the Red Sox's success, and he has yet to get a hit this season and has 15 strikeouts. Triston Casas hasn’t been much better, with just one hit and seven strikeouts. The value is with the Orioles and the better price.