Chicago Cubs vs Athletics Prediction 3/31/25 MLB Picks

Athletics Betting Preview

The Athletics are 2-2 on the year and play the Rockies, Padres, and Mets next. The Athletics are batting .211 on the season, have a .276 OBP, and a .391 slugging percentage. The Athletics' pitching staff has a 1.59 ERA and a 1.06 WHIP. Tyler Soderstrom leads the Athletics with 7 hits and 4 RBI, while Jacob Wilson and Brent Rooker have combined for 8 hits and 3 RBI.

Joey Estes gets the ball for the Athletics, and he was 7-9 with a 5.01 ERA and 92 strikeouts last season. This will be Estes’s second career game against the Chicago Cubs.

Why the Athletics will win

• The Athletics have won six of their last seven games as underdogs against National League opponents following a road loss.
• The Cubs have lost three of their last four games as road favorites.
• The Athletics have covered the run line each of their last six night games against National League opponents that held a losing record.
• The Cubs have failed to cover the run line in four of their last five games as road favorites against American League opponents.
• The Cubs have trailed after 3 innings in three of their last four night games.

Why the Chicago Cubs will win

• The Cubs have won seven of their last eight road games against the Athletics.
• The Athletics have lost five of their last six home games after playing the previous day.
• The Athletics have failed to cover the run line in each of their last five home games after playing the previous day.
• The Cubs have covered the run line in each of their last four games as road favorites against AL West opponents.
• The Athletics have trailed after 5 innings in three of their last four home openers.
• The Cubs have led after 3 innings in four of their last five night games against AL West opponents.

Chicago Cubs vs Athletics Prediction

The Chicago Cubs are off to a disappointing start where the offense hasn’t shown up, and the pitching has been getting rocked. I’m not excited with what I’ve seen in the small sample size, and Brown wasn’t good in his season debut. The Athletics held their own in their season opener, the pitching has been strong, and now they make their debut at Sutter Health Park. It’s not the A’s permanent home, but I’m sure Sacramento will show up for opening day and take advantage of being able to see MLB baseball. Dodger Stadium and Angel Stadium are six hours away from Sacramento, so this is a chance I’m sure many are excited about. I expect a packed house with some energy. Give me the Athletics.