Cleveland Guardians vs San Diego Padres Prediction 3/31/25 MLB Picks

-Recent Betting trends and streaks involving Cleveland

-Recent Betting trends and streaks involving San Diego 

-Recent betting trends in games played between Cleveland and San Diego

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Guardians and Padres 

Solid Start for the Guardians

It’s been a solid start for the Guardians, and they come into this game with a 2-1 record overall. On Sunday, the Guardians' pitching gave up only two runs against the Kansas City Royals, and they came out on top. The Guardians scored six runs, including two each in the 5th and sixth innings, to secure the win. Steven Kwan finished with three hits and one RBI. Tanner Bibee got the start, and he was strong, going 5.2 innings and giving up two hits and zero runs. The two runs given up on Sunday ended up being unearned. 

Kyle Mazard has hit two home runs and driven in six RBIs. Luis L Ortiz will get the start for the Guardians after spending the last couple of seasons with the Pittsburgh Pirates. In 37 games last year, he finished with a 7-6 record and an ERA of 3.32.

Why the Guardians Will Beat the Padres

• The Guardians have won four of their last six games as underdogs against the Padres.
• The Padres have lost four of their last five night games against the Guardians following a win.
• The Padres have failed to cover the run line in each of their last five night games following a win.
• The underdogs have covered the run line in six of the Padres' last seven games at Petco Park.

What a Start for the Padres

It has been quite the start for the Padres, and they have had a perfect record at 4-0. On Sunday, they played on Sunday Night Baseball against the Atlanta Braves, and they secured the 5-0 victory. The Padres' pitching gave up only one hit, and they were cruising all night. Nick Pivetta went seven innings and gave up only one hit. Fernando Tatis Jr is getting the bat going, and he finished with two hits and one RBI. 

Kyle Hart, who is back in the major leagues after being out for a while, will start for the Padres. In 2020, with the Boston Red Sox, he finished with a 0-1 record and an ERA of 15.15. 

Total Runs Facts

• Five of the Padres' last six games as favorites against American League opponents have gone UNDER the total runs line.
• Five of the Guardians' last six games against National League opponents have gone UNDER the total runs line.
• The 'Inning 1 OVER 0.5 runs' market has hit in each of the Padres' last six games as home favorites.
• The 'Inning 1 UNDER 0.5 runs' market has hit in seven of the Guardians' last eight games as road underdogs.

Cleveland Guardians vs San Diego Padres Prediction

Give me the Guardians here. Not only did the Padres have the Sunday Night Baseball game, but they now have to face off against the Guardians when there is a clear pitching disadvantage. Ortiz was solid for the Pirates last season, and getting even more run support with the Guaridans will help the record even more. The Guardians' offense is going to get to Hart early and often, and they will lean on the offense, plus the good pitching, to come out on top. Back the Guardians on the money line.