Nebraska vs Michigan State Prediction 9/26/2026 Today’s College Football Picks

The Nebraska Cornhuskers and Michigan State Spartans meet Saturday in week 4 college football action at Spartan Stadium. Here’s a Nebraska vs. Michigan State Prediction. This article will include a Nebraska vs. Michigan State Pick.

Nebraska Cornhuskers Betting Preview

The Nebraska Cornhuskers beat Bowling Green and North Dakota, and they play Maryland next. Nebraska looks for its first 4-0 start since the 2016 season. Anthony Colandrea is completing 68.8 percent of his passes for 692 yards, 8 touchdowns, and 1 interception. Jacory Barney Jr. and Kwazi Gilmer have combined for 349 receiving yards and 5 touchdowns, while Mekhi Nelson has 5 receptions.

The Nebraska Cornhuskers’ ground game is averaging 263 yards per contest, and Jamal Rule leads the way with 329 yards and 5 touchdowns. Defensively, Nebraska is allowing 11.7 points and 225.7 yards per game. Jamir Conn leads the Nebraska Cornhuskers with 16 tackles, Riley Van Poppel has 2 sacks, and Rex Guthrie has 1 interception.

Michigan State Spartans Betting Preview

The Michigan State Spartans beat Eastern Michigan, lost to Notre Dame, and play Wisconsin next. The Michigan State Spartans have won 3 of their last 4 games. Alessio Milivojevic is completing 66.2 percent of his passes for 540 yards, 3 touchdowns, and 2 interceptions. Rodney Bullard Jr. and Jayden Savoury have combined for 311 receiving yards and 1 touchdown, while Chrishon McCray has 11 receptions.

The Michigan State Spartans’ ground game is averaging 150.7 yards per contest, and Cam Edwards leads the way with 288 yards and 3 touchdowns. Defensively, Michigan State is allowing 18 points and 295.7 yards per game. Devin Vaught leads the Michigan State Spartans with 18 tackles, Eli Coenen has 3 sacks, and Kenny Soares Jr. has 1 interception.

Why the Michigan State Spartans will win

• Michigan State has won each of its last five September home games against non-AP-ranked teams.
• Nebraska has lost six of its last seven games against teams from Michigan.
• Nebraska has failed to cover the spread in eight of its last nine games against teams from Michigan.
• Michigan State has covered the spread in five of its last six games against conference opponents.
• Nebraska has lost the first half in nine of its last 12 games against teams from Michigan.

Why the Nebraska Cornhuskers will win

• Nebraska has won each of its last 10 September games as a favorite against non-AP-ranked teams.
• Michigan State has lost nine of its last 10 games against conference opponents.
• Michigan State has failed to cover the spread in seven of its last eight home games in September.
• Nebraska has covered the spread in seven of its last eight September games as a favorite against non-AP-ranked teams.
• The favorite has won the first half in 12 of Michigan State’s last 13 games.

Total Points Facts

• Each of Nebraska’s last four road games in September have gone UNDER the total points line.
• Each of Michigan State’s last four September games as a home underdog have gone UNDER the total points line.

Michigan State Spartans Player Prop Facts

• Heading into Week 4, Liam Boyd ranks T10th amongst FBS players for made field goals (6) this season.

Nebraska Cornhuskers Player Prop Facts

• Heading into Week 4, Anthony Colandrea ranks T6th in the league for TD: INT ratio (8.00) this season.

Matchup/League Facts

• Michigan State ranks T22nd among FBS teams for 1st downs against this season (43).
• Michigan State ranks T110th among FBS teams for red zone percentage against this season (100.0).
• Nebraska has recorded the most home wins by a margin of 20+ points of any FBS team this season (3).
• Nebraska has recorded the equal-most home wins by a margin of 25+ points of any FBS team this season (3).

Nebraska vs Michigan State Prediction

I know everybody is down on Michigan State, but this team still defends and gave Notre Dame a much tougher time than many originally thought. Michigan State has issues offensively, but this program still has heart and tries to compete. Nebraska hasn’t played anybody and is getting too much respect on the road. I’m just not there where I’m going to lay 5.5 points on the road with the Cornhuskers. Also, the underdog has cashed 6 of the last 8 meetings between Nebraska and Michigan State. Give me Sparty and the points.

Randy Chambers's Pick: Michigan State +5.5