Wyoming vs South Dakota State Prediction 12/15/2025 Today’s College Basketball Picks

The Wyoming Cowboys and the South Dakota State Jackrabbits meet Monday in college basketball action from Sanford Pentagon in Sioux Falls. Here’s a Wyoming vs South Dakota State prediction. We will look at this from a betting perspective and determine the best Wyoming vs South Dakota State pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Wyoming Cowboys Betting Preview

Wyoming is looking pretty good overall this year. The Cowboys beat Northern State, Cal State Fullerton, Austin Peay and Portland in their first four games, then took a loss to Sam Houston. Since then it’s been a 4-1 run with a lone loss to Texas Tech among wins versus Norfolk State, Denver, Dartmouth and South Dakota. Over 10 games so far this year that gives the Cowboys an 8-2 overall run.

Back on Tuesday versus South Dakota, the Cowboys were up comfortably 48-32 by the break. Wyoming hit a 58-47 run the rest of the way and took the win 106-79 in the end. Nasir Meyer led the way on 26 points with seven boards and Damarion Dennis had 21 points with two assists. Adam Harakow added 10 points with two rebounds in 17 minutes of work as well.

South Dakota State Jackrabbits Betting Preview

Over on the South Dakota State side, they kicked off the year on a 4-2 run. The two losses in that time were versus Northern Iowa and Oregon. Otherwise it was wins over Merrimack, Dakota State, Peru State and Georgia State. The next five were a 2-3 stretch with losses to UC Irvine, Utah Valley and Idaho mixed with wins over Northern Arizona and Ball State.

On Friday versus Dakota Wesleyan, the Jackrabbits were up by 12 points going into the second half. South Dakota State hit a 52-32 run the rest of the way and pulled off the win 94-62 in the end. Kalen Garry had 20 points with five boards and three assist to lead the way while Joe Sayler had 16 points with seven boards and seven assists. Damon Wilkinson doubled up with 15 points and 11 rebounds in the win as well.

Wyoming Cowboys @ South Dakota State Jackrabbits Betting Trends: December 15, 2025

Why the South Dakota State Jackrabbits will win

• Wyoming has lost eight of its last nine night games against non-AP-ranked opponents at a neutral venue.
• South Dakota State has won each of its last five games against non-Conference opponents at Sanford Pentagon.
• South Dakota State has won the first half in five of its last six night games against the Mountain West Conference.

Why the Wyoming Cowboys will win

• Wyoming has won seven of its last eight games against the Summit League.
• South Dakota State has lost four of its last five night games against non-AP-ranked opponents at a neutral venue.

Wyoming vs South Dakota State Prediction

I’ll stick with Wyoming. The Cowboys didn’t have too much issue with an average South Dakota team in their last outing, hitting a nice 62.5 percent shooting with 47.4 percent (9-of-19) from outside and 17-of-21 (81 percent) from the line. the 32-22 rebounding edge, 21 team assists and 60-26 advantage in the paint helped push Wyoming to a big win in Laramie. That gives the Cowboys 70 or more points in every game this year and a whopping 199 combined points over their last two games alone. When their offense is cooking, Wyoming can hang with just about anyone—as evidenced by a four-point road loss to a great Texas Tech squad late last month.

As for South Dakota State, they rolled right past Dakota Wesleyan on Friday, hitting 55.6 percent from the field with 41.4 percent (12-of-29) from outside and a 49-24 rebounding edge. The Jackrabbits weren’t great from the line (12-of-23 for 52.2 percent) however, and had 12 total turnovers in the 32-point blowout win. That gives SD State 75 or more points in three of the last four games, a 3-1 run.

Andrew Jett's Pick: Wyoming Cowboys -4.5