Virginia Tech vs Louisville Prediction 1/24/2026 Today’s College Basketball Picks

The Virginia Tech Hokies and the Louisville Cardinals meet Saturday in college basketball action from the KFC Yum! Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Virginia Tech Hokies vs. Louisville Cardinals prediction.

Virginia Tech Hokies Recap

The Virginia Tech Hokies come into this game looking to add on to their 76-74 win over Syracuse last time out to sit at 15-5 this season. After this game, Virginia Tech will head home for a game against Georgia Tech.

Hokies Win Back-To-Back Games

Amani Hansberry leads Virginia Tech in scoring and rebounding with 16.3 PPG and 8.4 RPG along with 3.3 APG while Neoklis Avdalas has 14.6 PPG with 3.5 RPG and a team-high 5 APG to lead the Hokies in assists up to this point in the year. Tobi Lawal has 12.8 PPG and Jaden Schutt has 10.6 PPG while Ben Hammond’s added 10.1 PPG with 3.5 APG to cap off the group of double-digit scorers for Virginia Tech up to this point in the year. Tyler Johnson has 9.5 PPG with 5.3 RPG and Jailen Bedford has 8.3 PPG with 2.8 RPG as well this season. As a team, Virginia Tech is averaging 83.1 PPG on 47% shooting from the field, 35.9% from the foul line and 70.3% from the foul line this season.

Louisville Cardinals Recap

The Louisville Cardinals come into this game looking to add on top their 100-59 win over Pitt last time out to sit at 13-5 this season. After this game, Louisville will head on the road for a game against Duke.

Cardinals Alternate Wins & Losses In 4 Straight

Ryan Conwell leads the Cardinals in scoring with 19.2 PPG along with 4.6 RPG and 2.3 APG while Mikel Brown Jr. has 16.6 PPG with a team-high 5.1 APG to lead the Cardinals in assists and 3 RPG. Isaac McKneely’s added 11.3 PPG with 3.3 RPG and Sananda Fru has 10.7 PPG with 6.3 RPG to lead the Cardinals in rebounding and to round out the group of double-digit scorers for Louisville so far this season. J’Vonne Hadley has 9.9 PPG with 5 RPG while Adrian Wooley’s added 9.1 PPG with 4.6 RPG and Khani Rooths has 6.4 PPG with 4.4 RPG this season. As a team, Louisville is averaging 91.6 PPG on 47.5% shooting from the field, 36% from three and 76.5% from the foul line this season.

Virginia Tech Hokies @ Louisville Cardinals Betting Trends: January 24, 2026

Why the Louisville Cardinals will win

• Louisville has won each of its last 31 games as an AP-ranked team against a non-AP-ranked team at KFC Yum! Center.
• Virginia Tech has lost six of its last seven games against AP-ranked opponents.
• Louisville has won the first half in 17 of its last 18 games at KFC Yum! Center against non-AP-ranked opponents.

Why the Virginia Tech Hokies will win

• Virginia Tech has won six of its last seven day games.
• The road team has won the first half in each of the last four games between Virginia Tech and Louisville.

Total Points Facts

• Each of Virginia Tech’s last 16 road games against Conference opponents have produced a total of 159 or fewer points.
• Each of the last nine games between Virginia Tech and Louisville have produced a total of 144 or fewer points.

Matchup/League Facts

• Louisville ranks 4th among Division 1 teams for three-point field goals made per game this season (11.9).
• Louisville ranks 4th among Division 1 teams for three-point field goal attempts per game this season (33.9).
• Virginia Tech ranks 26th among Division 1 teams for opponent steals per game this season (5.3).
• Virginia Tech ranks 29th among Division 1 teams for opponent three-point percentage this season (29.5%).

Virginia Tech Hokies vs. Louisville Cardinals Prediction

I’m on the Hokies here. I think Louisville is the better team, but this is a ton of points to give to a capable VA Tech team that can still score and has been competitive in a lot of spots already this year. Give me the Hokies and the points in game that Louisville wins, but Virginia Tech covers.

Chris Ruffolo's Pick: Virginia Tech +12.5