Nov 14, 2025; Inglewood, California, USA; Southern California Trojans guard Rodney Rice (1) shoots a free throw during the first half of the Hall of Fame Series game against the Illinois State Redbirds at Intuit Dome. Mandatory Credit: Kiyoshi Mio-Imagn Images
Kiyoshi Mio-Imagn Images

USC vs Seton Hall Prediction 11/25/2025 Today’s College Basketball Picks

Pick details

Seton Hall (6-0) vs USC (5-0)

05:00 PM EST

The Line: Betting Odds: — Over/Under:

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In this article we will formulate a USC vs Seton Hall prediction for this College Basketball game on Tuesday, November 25th at the Lahaina Civic Center in Maui, Hawaii. Let’s take a look at the prediction for this College Basketball matchup.

USC Trojans Betting Preview

The USC Trojans are 5-0 this season after they defeated Boise State by a score of 70-67 in their last game. USC led 34-32 at halftime and scored 36 points in the second half to secure the very close win. The Trojans shot 44% from the field, 48% on three pointers, and 65% on free throws in the game. Rodney Rice led USC with 27 points and three assists, while Chad Baker-Mazara added 11 points and eight rebounds in the win. 

Prior to that win, USC defeated Troy in overtime by a score of 107-106 and Illinois State by a score of 87-67. The Trojans have scored 100.5 points per game with 43.5 rebounds and 22.8 assists per game, while they have allowed 80.0 points against per game this season. Chad Baker-Mazara is averaging 22.5 points and 6.8 rebounds per game, while Rodney Rice is averaging 20.5 points and 7.8 assists per game for the Trojans. USC is shooting 47.5% from the field, 70.6% on free throws, and 34% on three pointers this season. 

Seton Hall Pirates Betting Preview

The Seton Hall Pirates are 6-0 this year after they defeated NC State by a score of 85-74 in their last game. Seton Hall led 35-33 at halftime and added 50 points in the second half in the upset win. The Pirates shot 52% from the field, 32% on three pointers, and 83% on free throws in the game. AJ Staton-McCray led Seton Hall with 22 points and eight rebounds, while Mike Williams added 14 points and six rebounds in the win. 

Prior to that game, Seton Hall defeated New Haven by a score of 68-45 and Monmouth by a score of 70-58. The Pirates have scored 73.0 points per game with 38.2 rebounds and 13.6 assists per game, while they have allowed 54.6 points against per game this season. Tajuan Simpkins is averaging 13.2 points and 4.0 rebounds per game, while AJ Staton-McCray is averaging 10.4 points and 3.4 rebounds per game for the Pirates. Seton Hall is shooting 41.7% from the field, 75.2% on free throws, and 33% on three pointers this year. 

Why the Seton Hall Pirates will win

  • Seton Hall has won each of its last six games against non-Conference opponents.
  • USC has lost three of its last four games against the Big East Conference at neutral venues.

Why the USC Trojans will win

  • USC has won seven of its last eight games against non-AP-ranked opponents.
  • Seton Hall has lost each of its last three games against the Big Ten Conference.
  • Seton Hall has lost the first half in three of its last four games against non-AP-ranked opponents at a neutral venue.

USC vs Seton Hall Prediction 

Both of these teams come into this matchup after winning on Monday afternoon and they are both undefeated on the season. USC has had back to back close calls against Troy and Boise State, but they are shooting 47% from the field. Seton Hall is shooting just 42% from the field and they aren’t great offensively, but their defense is elite. I haven’t seen a line for this game yet, but USC should be a slight favorite. With that being said, I think Seton Hall has all of the momentum and with their defense, I like them with the points.

David Racey's Pick: Seton Hall ATS

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