Siena vs Holy Cross Prediction 11/24/2025 Today’s College Basketball Picks

In this article, we will formulate a Siena vs Holy Cross Prediction for this College Basketball game on Monday, November 24th. Let’s take a look at the prediction for this College Basketball matchup.

Holy Cross Crusaders Preview

Holy Cross has a 1-5 record this season and are tied for 9th place in the Patriot conference. They are 3-3 ATS, 2-4 in Over/Under and have a 0-0 home record and a 0-5 away record. Holy Cross is coming off a 66-79 away loss against Sacred Heart and will face Worcester State, Northeastern and Fordham next.

Offensively, Holy Cross averages 64 points per game, which ranks 352nd in the nation, while defensively, they allow 80 points per game (287th). The Crusaders shoot with 42% from the field (312th), and with 31% from beyond the arc (272nd). They shoot with 67% from the free throw line (287th), and grab 30 rebounds per game (351st), while dishing out 10 assists per game (357th) and committing 13 turnovers per game (204th).

Tyler Boston leads Holy Cross in scoring, with an average of 14.7 points per game. Joe Nugent follows with 14 points and 4 rebounds per game, while Aiden Disu adds 8 points and 4 rebounds per game.

Siena Saints Preview

Siena has a 3-2 record this season and are tied for 7th place in the MAAC conference. They are 3-2 ATS, 1-4 in Over/Under and have a 2-1 home record and a 1-1 away record. Siena is coming off a 73-63 home win against Albany (NY) and will face Longwood and American next.

Offensively, Siena averages 70 points per game, which ranks 306th in the nation, while defensively, they allow 64 points per game (49th). The Saints shoot with 44% from the field (242nd), and with 26% from beyond the arc (345th). They shoot with 78% from the free throw line (37th), and grab 35 rebounds per game (256th), while dishing out 13 assists per game (245th) and committing 11 turnovers per game (104th).

Gavin Doty leads Siena in scoring, with an average of 16.8 points and 5.2 rebounds. Tasman Goodrick follows with 12.2 points and 9.4 rebounds per game, while Justice Shoats adds 10 points and 5.8 assists per game.

Siena Saints @ Holy Cross Crusaders Betting Trends: November 24, 2025

Why the Holy Cross Crusaders will win

• Siena has lost five of its last six road games following a home win.
• Holy Cross has won each of its last three night games at Hart Center at the Luth Athletic Complex following a road loss.

Why the Siena Saints will win

• Holy Cross has lost each of its last 10 Monday games against non-Conference opponents.
• Siena has won four of its last five games against Holy Cross.
• Holy Cross has lost the first half in each of its last six home games against the Metro Atlantic Athletic Conference.

Total Points Facts

• Seven of Holy Cross’ last eight games against the Metro Atlantic Athletic Conference have produced a total of 139+ points.
• Ten of Siena’s last 12 night games against the Patriot League have produced a total of 140+ points.

Matchup/League Facts

• Holy Cross ranks 365th among Division 1 teams for blocks per game this season (0.3).
• Holy Cross ranks 359th among Division 1 teams for opponent free throw percentage this season (80.4%).
• Siena ranks 365th among Division 1 teams for three-point field goals made per game this season (3.8).
• Siena ranks 363rd among Division 1 teams for three-point field goal attempts per game this season (14.4).

Siena vs Holy Cross Prediction

In this Siena vs Holy Cross Prediction, Siena is coming as -8.5 road favorites. Holy Cross has been terrible this season, with just one win in their six games played and have a bottom-15 offense in the country and an abysmal -16 point differential. On the flip side, Siena has a top-50 defense in the country and a +6 point differential and I expect them to get the job done in this matchup. Take Siena and lay the points on the road.

Nikos Lagouretos's Pick: Siena -8.5