Santa Clara vs Xavier Prediction 11/10/2025 Today’s College Basketball Picks

In this article we will formulate a Santa Clara vs Xavier prediction for this College Basketball game on Monday, November 10th at the Cintas Center in Cincinnati, Ohio. Let’s take a look at the prediction for this College Basketball matchup.

Santa Clara Broncos Betting Preview

The Santa Clara Broncos are 2-0 this year after they defeated McNeese by a score of 79-67 in their last game. Santa Clara led 37-33 at halftime and added 42 points in the second half for the win. The Broncos shot 39.4% from the field, 38.7% on three pointers, and 60% on free throws in the game. Santa Clara out rebounded McNeese by a total of 47-28, recorded 18 assists, and committed 15 turnovers in the win. Elijah Mahi led Santa Clara with 19 points and four rebounds, while Sash Gavalyugov added 19 points and three rebounds in the game. 

Prior to that game, Santa Clara defeated a non-D1 team by a score of 83-53 to start the season. The Broncos have scored 81.0 points per game with 47 rebounds and 20 assists per game, while they have allowed 60.0 points against per game this season. Elijah Mahi is averaging 16.5 points, 3.5 rebounds, and 2.5 assists per game, while Sash Gavalyugov is averaging 13.5 points and 2.5 rebounds per game. Santa Clara is shooting 43.6% from the field, 56.3% on free throws, and 32.8% on three pointers this year. 

Xavier Musketeers Betting Preview

The Xavier Musketeers are 2-0 this season after they defeated Le Moyne by a score of 74-69 in their last game. Xavier led 43-36 at halftime, but they were outscored 33-31 in the second half in the narrow win. The Musketeers shot 42.4% from the field, 52% on three pointers, and 68.8% on free throws in the game. Xavier was out rebounded by a total of 33-31, recorded 20 assists, and committed 11 turnovers in the win. Malik Messina-Moore led Xavier with 17 points and five assists, while Roddie Anderson III added 15 points and three rebounds in the game. 

Prior to that game, Xavier defeated Marist by a score of 66-62 to start their season. The Musketeers have scored 70.0 points per game with 31.0 rebounds and 16.5 assists per game, while they have allowed 65.5 points against per game this year. Malik Messina-Moore is averaging 16.5 points and 3.5 assists per game, while Tre Carroll is averaging 11.0 points and 4.5 rebounds per game. Xavier is shooting 38.4% from the field, 70.8% on free throws, and 39.2% on three pointers this season. 

Why the Xavier Musketeers will win

• Xavier has won each of its last nine games at Cintas Center.

Why the Santa Clara Broncos will win

• Santa Clara has won four of its last five night games against non-Conference opponents.

Total Points Facts

• Each of Xavier’s last nine home games against non-AP-ranked opponents have produced a total of 154 or fewer points.
• Three of Santa Clara’s last four night games against non-Conference opponents have produced a total of 163+ points.

Santa Clara vs Xavier Prediction 

Both of these teams come into this matchup with a 2-0 record to start the season, but Xavier will have the home court advantage. The Musketeers have only won their first two games by a combined nine points, so they have not been very impressive to start the campaign. Santa Clara did get a nice double digit win over McNeese in their last game, but they shot the ball under 40% in that game. Xavier is shooting just 38.4% from the field in their first two games, so both sides are struggling to make shots. I am going to give the edge to Xavier at home, but I am not impressed with them and could easily see them losing.

David Racey's Pick: Xavier -2.5