Pittsburgh vs Penn State Prediction 12/21/2025 Today’s College Basketball Picks

In this article, we will formulate a Penn State vs Pittsburgh Prediction for this College Basketball game on Sunday, December 21st. Let’s take a look at the prediction for this College Basketball matchup.

Pittsburgh Panthers Preview

Pittsburgh Panthers have a 6-6 record this season and are sitting in 16th place of the ACC. They have a 5-1 home record and are coming off a 103-63 home win against Binghamton. Their previous three games were a 79-61 away loss against Villanova, an 80-73 home loss against Hofstra, and an 81-73 home loss against Texas A&M.

Offensively, Pittsburgh averages 73.5 points per game, while allowing 69.6 points per game defensively. The Panthers shoot with 45% from the field and grab 35.7 rebounds per game, while dishing out 13.2 assists per game. They average 3.8 blocks per game and 6.6 steals per game defensively.

Cameron Corhen leads Pittsburgh in scoring, with an average of 13.7 points per game, while shooting with 54.1% from the field and 69.1% from the free throw line. Cameron Corhen also leads the team in rebounds with 8.7 per game, while Damarco Minor adds a team-high 3.3 assists per game.

Penn State Nittany Lions Preview

Penn State Nittany Lions have an 8-3 record this season and are sitting in 14th place of the Big Ten. They have a 5-1 home record and are coming off a 76-72 home loss against then No. 9 ranked Michigan State. Their previous three games were a 113-72 away loss against Indiana, an 87-76 home win against Campbell, and a 90-59 home win against Seton Hall.

Offensively, Penn State averages 81.1 points per game, while allowing 74.5 points per game defensively. The Nittany Lions shoot with 49.5% from the field and grab 31.5 rebounds per game, while dishing out 14 assists per game. They average 1.6 blocks per game and 8.3 steals per game defensively.

Kayden Mingo leads Penn State in scoring, with an average of 15 points per game. Kayden Mingo also leads the team in assists with 4.4 per game, while Josh Reed adds a team-high 4.1 rebounds per game.

Pittsburgh Panthers @ Penn State Nittany Lions Betting Trends: December 21, 2025

Why the Penn State Nittany Lions will win

• Penn State has won 12 of its last 13 games against non-Conference opponents.
• Pittsburgh has lost seven of its last eight day games.
• Pittsburgh has lost the first half in each of its last four day games.

Why the Pittsburgh Panthers will win

• Penn State has lost each of its last four day games against the Atlantic Coast Conference.
• Pittsburgh has won five of its last six day games against non-AP-ranked opponents at a neutral venue.
• Penn State has lost the first half in each of its last four day games against the Atlantic Coast Conference.

Total Points Facts

• Eight of Penn State’s last nine games have produced a total of 148+ points.
• Four of Pittsburgh’s last five games at a neutral venue have produced a total of 144 or fewer points.

Penn State vs Pittsburgh Prediction

In this Penn State vs Pittsburgh Prediction, Pittsburgh is coming as -1.5 home favorites. Penn State has a better overall record this season, while Pitt has lost both of its road games and this game is taking place in a neutral site. Both teams have not been in the best of forms lately, as Pitt is 1-3 in its last 4 games and Penn State is coming off back-to-back losses, so I see no value on either side. Both teams have been playing some high-scoring games lately, as they are a perfect 7-0 to the over in their last 7 games combined, so I expect another high-scoring affair today. Take the over 146.5 points.

Nikos Lagouretos's Pick: Over 146.5