Mercer vs Clemson Prediction 12/13/2025 Today’s College Basketball Picks

The Mercer Bears and the Clemson Tigers meet Saturday in college basketball action from the Littlejohn Coliseum. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Mercer Bears vs. Clemson Tigers prediction.

Mercer Bears Recap

The Mercer Bears come into this game looking to build on their 100-50 win over subdivision Oglethorpe last time out to sit at 7-2 this season. After this game, Mercer will take on UCF on the road.

Bears Win 5 In A Row

Baraka Okojie leads Mercer in scoring with 17.7 PPG and in assists with 6 APG along with 4.4 RPG while Quinton Perkins II has 13.1 PPG with 2.9 APG. Armani Mighty has 13.3 PPG with 8.3 RPG and Zaire Williams has 13 PPG with 3.4 RPG to cap off the group of double-digit scorers for Mercer so far this season. Kyle Cuffe Jr. has 8.4 PPG and Brady Shoulders has 8.4 PPG with a team-high 7.6 RPG to lead Mercer in rebounding up to this point in the year. As a team, Mercer is averaging 83.4 PPG on 45% shooting from the field, 35.8% from three and 72.3% from the foul line this season.

Clemson Tigers Recap

The Clemson Tigers come into this game looking to shake off their 67-64 loss at the hands of BYU last time out to sit at 7-3 this season. After this game, Clemson will take on South Carolina at home.

Tigers Lose Back-To-Back Games

Going into the BYU matchup, RJ Godfrey leads the Tigers in scoring and rebounding with 12.1 PPG and 6.4 RPG along with 2.3 APG while Carter Welling has 10.6 PPG with 6.2 RPG this season. Jestin Porter has 10.2 PPG with 2.1 RPG to cap off the trio of double-digit scorers for Clemson so far this season. Dillon Hunter has 9.2 PPG with 3.6 RPG and 2.7 APG while Nick Davidson has 8 PPG with 4.9 RPG and Jake Wahlin has 8 PPG with 4.8 RPG as well this season. Zac Foster’s added 7.8 PPG with 2.9 RPG and 2.9 APG as well to lead the Tigers in assists so far this season. As a team, Clemson is averaging 85.1 PPG on 46.3% shooting from the field, 32.8% from three and 74.9% from the foul line this season.

Mercer Bears @ Clemson Tigers Betting Trends: December 13, 2025

Why the Clemson Tigers will win

• Clemson has won each of its last 12 games against the Southern Conference.
• Mercer has lost three of its last four games against the Atlantic Coast Conference.
• Clemson has won the first half in each of its last 14 games at Littlejohn Coliseum against non-AP-ranked opponents.

Why the Mercer Bears will win

• Mercer has won seven of its last eight games.
• Clemson has lost three of its last four day games against non-Conference opponents.

Total Points Facts

• Thirty-nine of Clemson’s last 43 day games at Littlejohn Coliseum have produced a total of 152 or fewer points.
• Five of Mercer’s last six road day games against non-Conference opponents have produced a total of 172+ points.

Matchup/League Facts

• Clemson ranks 5th among Division 1 teams for turnover percentage this season (11.2%).
• Clemson ranks 9th among Division 1 teams for turnovers per game this season (9.1).
• Mercer ranks 356th among Division 1 teams for opponent field goal attempts per game this season (66.1).
• Mercer ranks 18th among Division 1 teams for steals per game this season (10.3).

Mercer Bears vs. Clemson Tigers Prediction

I’m on Mercer and the points here. I get why Clemson’s a big favorite at home, but they’re just coming off of the complete collapse against BYU that culminated in a buzzer-beater loss at the hands of the Cougars and this is a fairly quick turnaround to face Mercer of all teams, even at home. The Bears were competitive against a really solid Tennessee team on the road in Knoxville earlier this season and I think Mercer can at least compete here too. Give me Mercer and the points.

Chris Ruffolo's Pick: Mercer +21.5