Grand Canyon vs Wyoming Prediction 12/20/2025 Today’s College Basketball Picks

In this article, we will formulate a Grand Canyon vs Wyoming Prediction for this College Basketball game on Saturday, December 20th. Let’s take a look at the prediction for this College Basketball matchup.

Wyoming Cowboys Preview

Wyoming Cowboys have a 9-2 record this season and are sitting on the 5th place of the Mountain West. They have a 8-0 home record and are coming off a 87-72 home win against South Dakota State. Their previous three games were a 106-79 home win against South Dakota, a 93-80 home win against Dartmouth and a 72-76 away loss against Texas Tech.

Offensively, Wyoming averages 87.9 points per game, while allowing 71.7 points per game defensively. The Cowboys shoot with 50% from the field and grab 40.7 rebounds per game, while dishing out 16.2 assists per game. They average 2.4 blocks per game and 8.1 steals per game defensively.

Leland Walker leads Wyoming in scoring with an average of 14 points per game and adds a team-high 4.1 assists per game, while shooting with 47.9% from the field and 77.3% from the free throw line. Khaden Bennett is the team’s leading rebounder with 5.1 per game.

Grand Canyon Lopes Preview

Grand Canyon Lopes have a 6-4 record this season and are sitting on the 8th place of the Mountain West. They have a 0-1 away record and are coming off a 82-61 home win against Coastal Carolina. Their previous three games were a 78-84 home loss against Oklahoma State, a 67-45 home win against Stetson and a 46-59 home loss against Iowa.

Offensively, Grand Canyon averages 74.9 points per game, while allowing 67.7 points per game defensively. The Lopes shoot with 43% from the field and grab 38.1 rebounds per game, while dishing out 14.3 assists per game. They average 2.8 blocks per game and 6.3 steals per game defensively.

Jaden Henley leads Grand Canyon in scoring, with an average of 16.6 points per game, while shooting with 43.1% from the field and 85.5% from the free throw line. Nana Owusu-Anane is the team’s leading rebounder with 9.6 per game and adds a team-high 2.4 assists per game.

Grand Canyon Antelopes @ Wyoming Cowboys Betting Trends: December 20, 2025

Why the Wyoming Cowboys will win

• Wyoming has won each of its last eight home games.
• Grand Canyon has lost four of its last five road games against Conference opponents.
• Wyoming has won the first half in five of its last six home games.

Why the Grand Canyon Antelopes will win

• Wyoming has lost each of its last seven day games against Conference opponents.
• Grand Canyon has won each of its last three games when playing with a rest advantage.
• Wyoming has lost the first half in seven of its last eight day games against Conference opponents.

Grand Canyon vs Wyoming Prediction

In this Grand Canyon vs Wyoming Prediction, Wyoming is coming as -3.5 home favorites. Wyoming has been the better team this season, as they have just two losses in their 11 games played and have been undefeated at home. They are also playing their 9th game at home, out of their 13 overall this season and are 4-1 against the spread in their last 5 games, while Grand Canyon is 2-5 against the spread in its last 7. Wyoming has a superior offense, scoring 13 points per game more than Grand Canyon and has a +16.2 point differential this season, so I expect them to get the job done at home easily. Take Wyoming and lay the points in this one.

Nikos Lagouretos's Pick: Wyoming -3.5