Creighton vs DePaul Prediction 1/21/25 College Basketball Picks

The Creighton Bluejays and the Depaul Blue Demons meet Tuesday in college basketball action from the Wintrust Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Creighton vs. Depaul prediction.

Creighton Recap

The Creighton Bluejays come into this game looking to build on a 68-63 win over UConn last time out to improve to 12-6 on the year. After this game, Creighton will head home for a game against Seton Hall.

Bluejays Win Third Straight

Ryan Kalkbrenner leads the Bluejays in scoring and rebounding with 17.7 PPG and 8.4 RPG while Steven Ashworth has 17 PPG with 4.1 RPG and a team-leading 6.8 APG to lead the Bluejays in the assist department up to this point in the year. Jamiya Neal has 11.7 PPG with 5.8 RPG and 4.3 APG to cap off the scoring in double figures for the Bluejays so far this season. Jackson McAndrew has 8.3 PPG with 3.9 RPG as well on the year for Creighton. As a team, Creighton is averaging 75.4 PPG on 46.9% shooting from the field, 34.8% from three, and 75.5% from the foul line so far this season.

Why the Creighton Bluejays will win

• Creighton has won each of its last 20 games against DePaul.
• DePaul has lost each of its last 19 home games against the Big East Conference.

Depaul Recap

The Depaul Blue Demons come into this game looking to add to their first conference win in two years after a 73-68 win over Georgetown last time out to improve to 10-9 on the year. After this game, Depaul will head on the road for a game against Butler.

Blue Demons Snap Five-Game Skid

Jacob Meyer leads the Blue Demons in scoring with 13.6 PPG along with 3.7 RPG while Isaiah Rivera has 10.1 PPG and CJ Gunn has 11.5 PPG and 3.2 RPG to round out the group of double-digit scorers for the Blue Demons so far this season. NJ Benson has 8.5 PPG with a team-high 5.8 RPG to lead Depaul on the glass so far this season. Conor Enright also has a team-high 6.7 APG to lead the Blue Demons in the assist department up to this point in the year. As a team, Depaul is averaging 77.1 PPG on 45.2% shooting from the field, 37.6% from three, and 71.5% from the foul line this season.

Why the DePaul Blue Demons will win

• Creighton has lost each of its last four road night games against the Big East Conference.
• DePaul has won five of its last six night games at Wintrust Arena against non-AP-ranked opponents.

Total Points Facts

• Ten of Creighton’s last 11 night games against the Big East Conference have produced a total of 147+ points.
• Eight of DePaul’s last 10 night games at Wintrust Arena have produced a total of 147+ points.

Creighton vs. Depaul Prediction

I’m on Creighton here. I just think Depaul’s getting too much love too soon for beating a Georgetown team without two of their biggest difference-makers in Epps and Sorber. Creighton hasn’t been one of my favorite teams, but there’s no denying how well they’re playing right now, and I don’t want to step in front of the Bluejays when Depaul is the only other alternative. There may be spots where Depaul holds some value, but in this game, it’s back to blindly fading the Big East dumpster fire that is the Depaul Blue Demons. Give me Creighton laying the points in this one.