Notre Dame vs Clemson Prediction 2/26/25 College Basketball Picks

The Notre Dame Fighting Irish are visiting the Clemson Tigers on Wednesday, February 26th at the Littlejohn Coliseum. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Notre Dame Fighting Irish vs Clemson Tigers Prediction. We will examine:

The Clemson Tigers’ recent form and player performance

The Notre Dame Fighting Irish’s recent form and player performance

Recent betting trends and streaks involving the Clemson Tigers

Recent betting trends and streaks involving the Notre Dame Fighting Irish

Recent betting trends in games played between the Notre Dame Fighting Irish and Clemson Tigers

A summary that ties it all together and produces a favorable betting outcome for the Notre Dame Fighting Irish vs Clemson Tigers game

Clemson Tigers Preview

The Clemson Tigers have a 22-5 record this season and are sitting in third place in the Atlantic Coast. The Tigers are coming off a 79-69 win over SMU. The Tigers are 17-10 against the spread, and 14-13 in over/under while having a 13-2 home record.

Offensively, Clemson is averaging 77.5 points per game, which ranks 89th in the nation. Defensively, they are allowing 66.5 points per game (45th). The Tigers shoot 46.9% from the field (68th) and 38.8% from beyond the arc, which is the 11th-best nationally. The Tigers shoot 76.9% from the free throw line (36th) and are grabbing 35.1 rebounds per game (192nd).

Chase Hunter leads Clemson in scoring this season, with an average of 17 points and 3 rebounds, while Ian Schieffelin adds 12.4 points and a team-high 9.4 rebounds per game.

Notre Dame Fighting Irish Preview

The Notre Dame Fighting Irish have a 12-15 record this season and are sitting in 12th place in the ACC. The Fighting Irish are coming off a 76-72 win over Pitt. The Fighting Irish are 11-14-2 against the spread, and 13-14 in over/under while having a 3-7 road record.

Offensively, Notre Dame is averaging 73.3 points per game, which ranks 209th in the nation. Defensively, they allow 71.9 points per game (187th). The Fighting Irish shoot 45.7% from the field (131st) and 36.2% from beyond the arc (69th). The Fighting Irish shoot 74.3% from the free-throw line (99th) and are grabbing 34.7 rebounds per game (225th).

Markus Button leads Notre Dame in scoring this season, with an average of 20.3 points, adding 3.4 rebounds and 3 assists, while Tre Davis adds 15.8 points and 5.4 rebounds per game. Notre Dame will meet Wake Forest after this game.

Why the Clemson Tigers will win

• Notre Dame has lost each of its last eight games against AP-ranked opponents.
• Clemson has won 23 of its last 24 Wednesday games at Littlejohn Coliseum.
• Clemson has won the first half in each of its last 10 games against non-AP-ranked opponents.

Why the Notre Dame Fighting Irish will win

• The road team has won four of Notre Dame’s last five games.
• The road team has won the first half in three of Clemson’s last four games.

Total Points Facts

• Each of Clemson’s last six night games against Conference opponents at Littlejohn Coliseum has produced a total of 148+ points.
• Ten of Notre Dame’s last 11 road night games against Conference opponents have produced a total of 135 or fewer points.

Notre Dame Fighting Irish vs Clemson Tigers Prediction

Notre Dame is 7-3 in their last 10 meetings against Clemson and is 8-2 against the spread. Under is 5-2 in their last 7 meetings, and in their previous meeting last season, Notre Dame won 69-62 at home, covering the spread, as the game went under the point total.

In this Notre Dame Fighting Irish vs Clemson Tigers Prediction, Clemson is coming as a -14.5 home favorites. Clemson is rightfully favored, as they have been the better team this season, and have been extremely good at home, while Notre Dame is struggling on the road. Clemson is coming red-hot in this matchup, as they are 9-1 in their last 10 games, and 8-2 against the spread, while on the other hand, Notre Dame is struggling, as they are 2-5 in their last 7 games and 1-7 against the spread in their last 8. The value here lies with the home team, so take the Clemson Tigers and lay the points at home.