Sep 20, 2025; Lincoln, Nebraska, USA; Michigan Wolverines quarterback Bryce Underwood (19) scrambles against the Nebraska Cornhuskers during the third quarter at Memorial Stadium. Mandatory Credit: Dylan Widger-Imagn Images

Wisconsin vs Michigan Prediction 10/4/2025 Today’s College Football Picks

Pick details

Wisconsin (2-2) vs Michigan (3-1)

October 4, 2025 at 12:00 PM EDT

The Line: Betting Odds: Michigan -16.5 — Over/Under: +42.5

(Get latest betting odds)

Wisconsin and Michigan meet Saturday in Week 6 college football action from Michigan Stadium. Here’s a Wisconsin vs Michigan prediction. We will look at this from a betting perspective and determine the best Wisconsin and Michigan pick. We will examine:

The Wisconsin Badgers’ recent form and player performance

The Michigan Wolverines’ recent form and player performance

Recent betting trends and streaks involving the Badgers

Recent betting trends and streaks involving the Wolverines

Recent betting trends in games played between Wisconsin and Michigan

A summary that ties it all together and produces a favorable betting outcome for the Wisconsin and Michigan game.

Big Time Game for Wisconsin


It’s a big time game for Wisconsin as they try to make a statement and put themself back in the Big Ten conversation. After winning the first two games of the season, Wisconsin is struggling and they have lost two games in a row. Two games ago against Alabama they won 38-14 and in the last game against Maryland they were knocked off 27-10. The offense just isn’t that explosive without Billy Edwards Jr under center, and it showed in a big way in the last game. Danny O’Neil got most of the playing time under center after Edwards went down with an injury and finished with 120 yards, zero touchdowns, and one interception on 14 completions. 

Wisconsin on the season is averaging 20.8 points while thier defense is giving up 18.8 points per game. The offense is ranked 109th in college football while the defense is ranked 38th. Wisconsin is coming off a bye week, but it’s still unclear at the time of this article if Billy Edwards Jr is going to be ble to go here. 

Why the Wisconsin Badgers will win

  • Wisconsin has won each of its last three road games in October.
  • Wisconsin has covered the spread in each of its last three road games in October.

Michigan Can’t Slip Up


Want to know HOW the Pros Bet?
Professional Bettor Demo: 👉 SEE IT NOW! 👈


Michigan knows they can’t slip up here, in a game they expect to win, or there is going to be even more chatter around this team. Michigan has one loss this season against Oklahoma, but they almost lost another game against Nebraska in the last game. Michigan scored 30 points against Nebraska and that was enough for the three-point victory. Even though they won, they still haven’t allowed Bryce Underwood to really air it out. In the last game, he completed 12 of his 22 passes for 105 yards. Justice Haynes ran wild and finished the game with 17 carries for 149 yards and a touchdown. 

Michigan on the season is averaging 35 points while their defense is giving up 17.8 points per game. The offense is ranked 42nd in all of college football while the defense is ranked 33rd. In this game, Michigan needs ot really try to pound the rock, and put the pressure on the ground. 

Why the Michigan Wolverines will win

  • Michigan has won 38 of its last 39 games against non-AP-ranked teams.
  • Wisconsin has lost each of its last 15 games as an underdog against AP-ranked teams.
  • Michigan has covered the spread in nine of its last 10 October games at Michigan Stadium.
  • Wisconsin has failed to cover the spread in five of its last six games as an underdog.
  • Michigan has won the first half in 31 of its last 40 games against conference opponents.

Wisconsin vs Michigan Prediction

Michigan is the much better team, but even this is too many points to lay. It’s unclear if Billy Edwards Jr is going to be able to go in this game, but even if he’s not able to, I like the Badgers. I still don’t believe Michigan is using Underwood the right way, and he hasn’t been dynamic through the passing game so far this season. Wisconsin might only score 17 points here, but the Wolverines’ offense isn’t going to be running away with it, and that will be the difference as the Badgers keep it within ten points. Back Wisconsin against the spread here. 

Shane Mickle's Pick: Wisconsin +16.5

Need More? Get Premium Picks

Hot Cappers

Latest Picks & Game Previews

  • San Francisco 49ers vs Los Angeles Rams Prediction 10/2/2025 Today’s NFL Picks

    October 02, 2025

  • Sam Houston State vs New Mexico State Prediction 10/2/2025 Today’s College Football Picks

    October 02, 2025

  • Charlotte vs South Florida Prediction 10/3/2025 Today’s College Football Picks

    October 03, 2025

  • Western Kentucky vs Delaware Prediction 10/3/2025 Today’s College Football Picks

    October 03, 2025

  • Colorado State vs San Diego State Prediction 10/3/2025 Today’s College Football Picks

    October 03, 2025

  • Clemson vs North Carolina Prediction 10/4/2025 Today’s College Football Picks

    October 04, 2025

  • Wisconsin vs Michigan Prediction 10/4/2025 Today’s College Football Picks

    October 04, 2025

  • Kentucky vs Georgia Prediction 10/4/2025 Today’s College Football Picks

    October 04, 2025

  • Air Force vs Navy Prediction 10/4/2025 Today’s College Football Picks

    October 04, 2025

  • Iowa State vs Cincinnati Prediction 10/4/2025 Today’s College Football Picks

    October 04, 2025