Western Kentucky running back Marvis Parrish (21) runs the ball, with offensive lineman Quincy Jenkins (63) providing cover, against Delaware Blue Hens linebacker Blake Matthews (10) during Delaware's first home CUSA football game, which was nationally televised, at Delaware Stadium in Newark on Oct. 3, 2025. Western Kentucky won 27-24.
Benjamin Chambers/Delaware News Journal / USA TODAY NETWORK via Imagn Images

Western Kentucky vs Louisiana Tech Prediction 10/21/2025 Today’s College Football Picks

Pick details

Western Kentucky (5-2) vs Louisiana Tech (4-2)

October 21, 2025 at 07:30 PM EDT

The Line: Betting Odds: Louisiana Tech -3 — Over/Under: +49.5

(Get latest betting odds)

The Western Kentucky Hilltoppers and Louisiana Tech Bulldogs meet Tuesday in college football action at Joe Aillet Stadium. Here’s a Western Kentucky vs Louisiana Tech Prediction. This article will include a Western Kentucky vs Louisiana Tech Pick.

Western Kentucky Hilltoppers Betting Preview

The Western Kentucky Hilltoppers beat Delaware, lost to FIU, and they play New Mexico State next. The Western Kentucky Hilltoppers have split their last 12 games. Maverick McIvor is completing 67.3 percent of his passes for 1,863 yards, 12 touchdowns, and 5 interceptions. Matthew Henry and KD Hutchinson have combined for 765 receiving yards and 6 touchdowns, while Moussa Barry has 18 receptions.


The Western Kentucky Hilltoppers ground game is averaging 122.3 yards per contest, and Marvis Parrish leads the way with 258 yards on 56 carries. Defensively, Western Kentucky is allowing 23.1 points and 403.1 yards per game. Jaylen Wester leads the Western Kentucky Hilltoppers with 39 tackles, Harper Holloman has 2 sacks and Jaylen Lewis has 2 interceptions.

Louisiana Tech Bulldogs Betting Preview


The Louisiana Tech Bulldogs beat UTEP, lost to Kennesaw State, and they play Sam Houston next. Louisiana Tech has won 6 of its last 10 games. Blake Baker is completing 61 percent of his passes for 649 yards, 3 touchdowns, and 1 interception. Eli Finley and Devin Gandy have combined for 440 receiving yards and 1 touchdown, while Marlion Jackson has 7 receptions.

The Louisiana Tech Bulldogs ground game is averaging 146.5 yards per contest, and Clay Thevenin leads the way with 261 yards and 3 touchdowns. Defensively, Louisiana Tech is allowing 17.2 points and 355.2 yards per game. Kolbe Fields leads the Louisiana Tech Bulldogs with 39 tackles, Mekhi Mason has 3 sacks and Jakari Foster has 3 interceptions.

Louisiana Tech Bulldogs Player Prop Facts

  • Heading into Week 9, Jakari Foster ranks T7th amongst FBS players for interceptions (3) this season.

Western Kentucky Hilltoppers Player Prop Facts

  • Heading into Week 9, Matthew Henry leads the Conference USA for receiving yards (435) this season.

Matchup/League Facts

  • Louisiana Tech ranks 131st among FBS teams for 1st downs this season (105).
  • Louisiana Tech ranks T7th among FBS teams for red zone percentage against this season (71.4).
  • Western Kentucky ranks 128th among FBS teams for rushing yards allowed per game this season (203.4).
  • Western Kentucky ranks T128th among FBS teams for 4th down conversion percentage this season (28.6).

Western Kentucky vs Louisiana Tech Prediction


You can talk yourself into Western Kentucky and the points, as it has a top-20 passing offense and LA Tech can’t defend the pass. However, Western Kentucky doesn’t run the ball or stop the run, and that’s usually a recipe for disaster on the road. Also, LA Tech has had an extra week to prepare for this game and that’s key given it’s also at home and laying a small number. Louisiana Tech has covered 6 of its last 8 games as a home favorite. We’re not getting enough points to give WKU a serious look in this spot. I’ll lay the tiny number with Louisiana Tech at home.

Randy Chambers's Pick: Louisiana Tech -3

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