West Virginia vs Houston Prediction 11/1/2025 Today’s College Football Picks

The West Virginia Mountaineers and the Houston Cougars meet in week 10 college football action from TDECU Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a West Virginia Mountaineers vs. Houston Cougars prediction.

West Virginia Mountaineers Recap

The West Virginia Mountaineers come into this game looking to rebound from a 23-17 loss at the hands of TCU last time out to sit at 2-6 this season. After this game, West Virginia will head home for a game against Colorado.

Mountaineers Drop 5 In A Row

Nicco Marchiol has thrown for 720 yards, 2 touchdowns and 2 INTs on 67.3% passing while Scotty Fox Jr. has thrown for 466 yards, 3 touchdowns and 2 picks on 59.1% passing and Khalil Wilkins has thrown for 176 yards, a TD and 2 INTs on 48.4% passing while also leading WVU in rushing with 243 yards and 2 touchdowns. Cam Vaughn leads West Virginia with 27 catches for 420 yards and 3 touchdowns while four more Mountaineers have 100+ receiving yards as well this season. On defense, Fred Perry leads West Virginia with 50 total tackles while Darrian Lewis and Chase Wilson each have 2 interceptions. As a unit, West Virginia’s defense has combined for 14 sacks and 8 interceptions this season.

Houston Cougars Recap

The Houston Cougars come into this game looking to add on to their 24-16 win over Arizona State last time out to sit at 7-1 this season. After this game, Houston will head on the road for a game against UCF.

Cougars Win 3 Straight

Conner Weigman has thrown for 1,581 yards, 12 touchdowns and 2 interceptions on 63.7% passing while Dean Connors has rushed for 586 yards and 4 TDs on the ground this season. Weigman has 354 rushing yards and 8 rushing TDs. Amare Thomas leads the Cougars with 535 receiving yards and 4 touchdowns while Stephon Johnson has 275 receiving yards and 2 TDs and Tanner Koziol has 450 receiving yards and 4 scores as well this season. On defense, Jalen Garner has a team-high 53 total tackles while Eddie Walls III has a team-high 5.5 sacks. As a unit, Houston’s defense has combined for 21 sacks and 6 interceptions so far this season.

West Virginia Mountaineers @ Houston Cougars Betting Trends: Week 10

Why the Houston Cougars will win

• West Virginia has lost each of its last 11 games against AP-ranked teams.
• Houston has won each of its last six games against non-AP-ranked teams.
• West Virginia has failed to cover the spread in 10 of its last 11 November games against AP-ranked teams.
• Houston has covered the spread in each of its last four games as a favorite in Texas.
• West Virginia has lost the first half in each of its last six games against conference opponents.

Why the West Virginia Mountaineers will win

• Houston has lost each of its last four November games against non-AP-ranked teams.
• The road team has won four of Houston’s last five games.
• Houston has failed to cover the spread in each of its last four November games as a favorite.
• The road team has covered the spread in three of Houston’s last four games.

Total Points Facts

• Each of Houston’s last five games against non-AP-ranked teams have gone OVER the total points line.
• Each of West Virginia’s last four road games against AP-ranked teams have gone OVER the total points line.

Houston Cougars Player Prop Facts

• Heading into Week 10, Dean Connors leads the Big 12 Conference for rush attempts (135) this season.

West Virginia Mountaineers Player Prop Facts

• Heading into Week 10, Cam Vaughn leads West Virginia for touchdowns (3) this season.

Matchup/League Facts

• Houston ranks 1st among FBS teams for Q3 opponent points per game this season (0.8).
• Houston is one of only seven FBS teams undefeated in road games this season (4-0).
• West Virginia ranks 134th among FBS teams for H1 points per game this season (6.4).
• West Virginia ranks 133rd among FBS teams for Q1 points per game this season (1.8).

West Virginia Mountaineers vs. Houston Cougars Prediction

I’m on Houston here. I think Houston might be one of my least favorite 7-1 teams I’ve laid eyes on, but they keep finding ways to get the job done and maybe this game is more of a fade of West Virginia more than anything else but I’m rolling with Houston in this one.