Sep 5, 2025; Evanston, Illinois, USA; Western Illinois Leathernecks defensive back Malini Ti'a (33) defends Northwestern Wildcats quarterback Preston Stone (8) during the second half at Northwestern Medicine Field at Martin Stadium. Mandatory Credit: David Banks-Imagn Images

UL Monroe vs Northwestern Prediction 10/4/2025 Today’s College Football Picks

Pick details

UL Monroe (3-1) vs Northwestern (2-2)

October 4, 2025 at 03:30 PM EDT

The Line: Betting Odds: Northwestern -11.5 — Over/Under: 41

(Get latest betting odds)

The Louisiana-Monroe Warhawks and the Northwestern Wildcats meet in week 6 college football action from Martin Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Louisiana-Monroe Warhawks vs. Northwestern Wildcats prediction.

Louisiana-Monroe Warhawks Recap

The Louisiana-Monroe Warhawks come into this game looking to build on a 28-16 win over Arkansas State last time out to sit at 3-1 this season. After this game, ULM will return to conference play for a game against the Coastal Carolina Chanticleers.

Warhawks Win Back-To-Back Games

Aidan Armenta has thrown for 444 yards, 5 touchdowns and 3 interceptions on 58.4% passing while Braylon McReynolds leads ULM in rushing with 309 rushing yards and 2 touchdowns and Dorian Lewis has 131 rushing yards so far this season. Jake Godfrey leads ULM with 110 receiving yards and 2 touchdowns while Tyler Griffin has a team-high 8 catches for 92 yards and a touchdown of his own so far this season. On defense, Noah Flemmings has a team-high 23 total tackles while Dylan Howell has a team-high 4 sacks and D’Arco Perkins-McAllister has 3 sacks so far this season. As a unit, Louisiana-Monroe’s defense has combined for 13 sacks and 4 interceptions so far this season.

Northwestern Wildcats Recap

The Northwestern Wildcats come into this game looking to build on their 17-14 win over UCLA in their last game to improve to 2-2 this season. After this game, Northwestern will head on the road for a game against Penn State.

Wildcats Looking For Consistency Ahead Of Penn State Tilt

Preston Stone has thrown for 656 yards, 4 touchdowns and 6 interceptions on 60.6% passing while Caleb Komolafe has a team-high 269 rushing yards and 2 touchdowns. Joseph Himon II also has 195 rushing yards while Griffin Wilde leads Northwestern’s receivers with 22 grabs for 311 yards and a touchdown so far this season. On defense, Robert Fitzgerald leads Northwestern with 36 total tackles while Mac Uihlein has 28 total tackles and a pair of interceptions. 

Louisiana-Monroe Warhawks @ Northwestern Wildcats Betting Trends: Week 6

Why the Northwestern Wildcats will win

  • Louisiana-Monroe has lost each of its last 11 road games in October.
  • Northwestern has won each of its last nine October games as a favorite.
  • Louisiana-Monroe has failed to cover the spread in five of its last six games as an underdog.
  • The favorite has covered the spread in six of Louisiana-Monroe’s last eight games.
  • Louisiana-Monroe has lost the first half in 30 of its last 32 road games against non-conference opponents.

Why the Louisiana-Monroe Warhawks will win


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  • Louisiana-Monroe has won each of its last three games against non-AP-ranked teams.
  • Northwestern has failed to cover the spread in five of its last six home games in October.
  • Louisiana-Monroe has covered the spread in three of its last four October games as an underdog.

Total Points Facts

  • Seven of Louisiana-Monroe’s last eight games as an underdog have gone OVER the total points line.
  • Each of Northwestern’s last four October games as a favorite have gone UNDER the total points line.

Northwestern Wildcats Player Prop Facts

  • Heading into Week 6, Caleb Komolafe leads Northwestern for touchdowns (2) this season.

Louisiana-Monroe Warhawks Player Prop Facts

  • Heading into Week 6, Dylan Howell leads the Sun Belt Conference for sacks (4.0) this season.

Matchup/League Facts

  • Northwestern has recorded the equal-most home wins by a margin of five points or less of any FBS team this season (1).
  • Northwestern has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
  • Louisiana-Monroe ranks T1st among FBS teams for red zone percentage this season (100.0).
  • Louisiana-Monroe ranks 131st among FBS teams for passing yards per game this season (125.5).

Louisiana-Monroe Warhawks vs. Northwestern Wildcats Prediction

I’m on the under here. I just think this game features two teams with below average quarterback play, as Aidan Armenta is a below average QB by even Sun Belt standards, and Preston Stone is lucky to be where he is considering how turnover-prone he’s been for much of the season. All in all, this just feels like a low-scoring 60-minute slopfest, where Northwestern has their eyes on Penn State and ULM can’t really do anything in a step up in class. Give me the under.

Chris Ruffolo's Pick: Under 41

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