Tennessee Volunteers quarterback Nico Iamaleava (8) throws during the second half of the College Football Playoff first round game against the Ohio State Buckeyes at Ohio Stadium in Columbus on Dec. 22, 2024. Ohio State won 42-17.
Adam Cairns/Columbus Dispatch / USA TODAY NETWORK via Imagn Images

Tennessee vs Kentucky Prediction 10/25/2025 Today’s College Football Picks

Pick details

Tennessee (5-2) vs Kentucky (2-4)

October 25, 2025 at 07:45 PM EDT

The Line: Betting Odds: Kentucky +9.5 — Over/Under: +54.5

(Get latest betting odds)

In this article, we will formulate a Tennessee vs Kentucky Prediction for this College Football Week 9 game on Saturday, October 25th. Let’s take a look at the prediction for this College Football matchup.

Kentucky Wildcats Preview

Kentucky has a 2-4 record this season and is sitting 16th in the SEC. They are 2-4 ATS, 4-2 in Over/Under and have a 2-2 home record and a 0-2 away record. Kentucky is coming off a 13-16 home loss against Texas and will face Auburn, Florida and Tennessee Tech next.

Offensively, Kentucky averages 22.5 points per game, ranking 103rd in the nation, while defensively, they allow 25.8 points per game, which is 82nd. Kentucky averages 342.2 total yards per game (186.5 passing and 155.7 rushing), while allowing 365 total yards per game (135.8 rushing and 229.2 passing).

Cutter Boley leads Kentucky with 885 passing yards with 64.2% completed passes and 4 touchdowns. Seth McGowan leads the team in rushing yards with 476, while Kendrick Law has a team-high 22 receptions for 199 receiving yards. Defensively, Alex Afari Jr. has a team-high 39 total tackles (23 of them solo), while Steven Soles Jr. leads the team in sacks, with 3.0, and Ty Bryant has a team-high 2 interceptions.

Tennessee Volunteers Preview

Tennessee has a 5-2 record this season and is sitting 6th in the SEC. They are 2-4-1 ATS, 5-2 in Over/Under and have a 3-1 home record and a 1-1 away record. Tennessee is coming off a 20-37 road loss against Alabama and will face Oklahoma, New Mexico State and Vanderbilt next.

Offensively, Tennessee averages 44.1 points per game, ranking 3rd in the nation, while defensively, they allow 30.4 points per game, which is 110th. Tennessee averages 511.0 total yards per game (310.7 passing and 200.3 rushing), while allowing 390.9 total yards per game (133.7 rushing and 257.1 passing).

Joey Aguilar leads Tennessee with 1,948 passing yards with 64.6% completed passes and 15 touchdowns. DeSean Bishop leads the team in rushing yards with 604, while Chris Brazzell II has a team-high 39 receptions for 602 receiving yards. Defensively, Arion Carter has a team-high 61 total tackles (20 of them solo), while Joshua Josephs leads the team in sacks, with 4.0, and Colton Hood has a team-high one interception.

Tennessee Volunteers @ Kentucky Wildcats Betting Trends: Week 9

Why the Kentucky Wildcats will win

  • Kentucky has won each of its last three games following an overtime loss.
  • Tennessee has lost three of its last four road games in October.
  • Kentucky has covered the spread in seven of its last eight games against AP-ranked teams.
  • Tennessee has failed to cover the spread in each of its last four games.

Why the Tennessee Volunteers will win

  • Tennessee has won each of its last 10 games against non-AP-ranked teams.
  • Kentucky has lost each of its last nine games against conference opponents.
  • Tennessee has covered the spread in each of its last six road games against Kentucky.
  • Kentucky has failed to cover the spread in each of its last six home games against teams from Tennessee.
  • Kentucky has lost the first half in each of its last five games against conference opponents.

Total Points Facts

  • Each of Tennessee’s last five games in October have gone UNDER the total points line.
  • Five of Kentucky’s last six home games against conference opponents have gone UNDER the total points line.

Kentucky Wildcats Player Prop Facts

  • Heading into Week 9, Steven Soles Jr. leads the Southeastern Conference for forced fumbles (2) this season.

Tennessee Volunteers Player Prop Facts

  • Heading into Week 9, Chris Brazzell II leads the Southeastern Conference for receiving touchdowns (7) this season.

Matchup/League Facts

  • Kentucky ranks 132nd among FBS teams for average point differential in second quarters this season (-6.2).
  • Kentucky ranks 125th among FBS teams for Q2 opponent points per game this season (11.2).
  • Tennessee has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
  • Tennessee ranks 1st among FBS teams for Q1 points per game this season (14.3).

Tennessee vs Kentucky Prediction

In their previous meeting last season, Tennessee won 28-18 at home, and are 8-2 in their last 10 meetings against the Wildcats, having won their last three visits in Kentucky. Over is 3-1 in their last 4 meetings.

In this Tennessee vs Kentucky Prediction, Tennessee is coming as -9.5-point road favorites, with the total set at 54.5 points. Both teams are coming into this matchup in opposite trajectories, as Kentucky has lost three straight games, while Tennessee is 3-1 in its last 4. Tennessee has been a beast offensively, having the third-best offense in the nation, scoring almost twice as many points as Kentucky, and winning by an average of 13.7 points this season. Tennessee has also been dominating this matchup in recent years, so I like them to get the job done on the road. Take Tennessee and lay the -9.5 points in this one.

Nikos Lagouretos's Pick: Tennessee -9.5

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