Sep 6, 2025; Dallas, Texas, USA; SMU Mustangs wide receiver Romello Brinson (3) celebrates during the game between the SMU Mustangs and the Baylor Bears at Gerald J. Ford Stadium. Mandatory Credit: Jerome Miron-Imagn Images

Stanford vs SMU Prediction 10/11/2025 Today’s College Football Picks

Pick details

Stanford (2-3) vs SMU (3-2)

October 11, 2025 at 12:00 PM EDT

The Line: Betting Odds: SMU -19.5 — Over/Under: +55.5

(Get latest betting odds)

The Stanford Cardinal and SMU Mustangs meet Saturday in college football action at Gerald J. Ford Stadium. Here’s a Stanford vs SMU Prediction. This article will include a Stanford vs SMU Pick.

Stanford Cardinal Betting Preview


The Stanford Cardinal lost to Virginia, beat San Jose State, and they play Florida State next. Stanford has lost 11 of its last 14 games. Ben Gulbranson is completing 60.3 percent of his passes for 1,167 yards, 5 touchdowns, and 3 interceptions. Bryce Farrell and CJ Williams have combined for 641 receiving yards and 1 touchdown, while Caden High has 14 receptions.

The Stanford Cardinal ground game is averaging 96.2 yards per contest, and Micah Ford leads the way with 347 yards and 3 touchdowns. Defensively, Stanford is allowing 29.4 points and 428.2 yards per game. Matt Rose leads the Stanford Cardinal with 40 tackles, Clay Patterson has 3 sacks and Collin Wright has 1 interception.

SMU Mustangs Betting Preview


The SMU Mustangs lost to TCU, beat Syracuse, and play Clemson next. SMU has split its last 8 games. Kevin Jennings is completing 71.4 percent of his passes for 1,411 yards, 13 touchdowns, and 6 interceptions. Romello Brinson and Jalen Cooper have combined for 707 receiving yards and 5 touchdowns, while Yamir Knight has 17 receptions.

The SMU Mustangs ground game is averaging 128 yards per contest, and T.J. Harden leads the way with 376 yards and 5 touchdowns. Defensively, SMU is allowing 24.8 points and 437.2 yards per game. Isaiah Nwokobia leads the SMU Mustangs with 37 tackles, Jeffrey M’ba has 3 sacks and Ahmaad Moses has 2 interceptions.

Why the SMU Mustangs will win

  • SMU has won each of its last 11 games against conference opponents at Gerald J. Ford Stadium.
  • Stanford has lost each of its last eight road games.
  • Stanford has failed to cover the spread in seven of its last eight road games.
  • The home team has covered the spread in five of Stanford’s last six games.
  • SMU has won the first half in each of its last nine games against conference opponents at Gerald J. Ford Stadium.
  • SMU has won the first quarter in eight of its last nine games against conference opponents at Gerald J. Ford Stadium.

Why the Stanford Cardinal will win

  • Stanford has won eight of its last nine October road games against non-AP-ranked teams.
  • SMU has failed to cover the spread in each of its last seven games.
  • The underdog has covered the spread in four of SMU’s last five games.
  • Stanford has won the first quarter in three of its last four games against conference opponents.

Total Points Facts

  • Six of SMU’s last seven games against non-AP-ranked teams have gone UNDER the total points line.
  • Four of Stanford’s last five games against conference opponents have gone OVER the total points line.

SMU Mustangs Player Prop Facts

  • Kevin Jennings has recorded 275+ passing yards in four consecutive games – equal-longest streak in the FBS, heading into Week 7.

Stanford Cardinal Player Prop Facts

  • Heading into Week 7, Micah Ford leads Stanford for touchdowns (3) this season.

Matchup/League Facts

  • SMU ranks 136th among FBS teams for passing yards allowed per game this season (323.4).
  • SMU has had a lower time of possession than its opponents in each of its last 14 games – longest active streak in the FBS.
  • Stanford ranks 135th among FBS teams for passing yards allowed per game this season (315.0).
  • Stanford ranks T127th among FBS teams for Q3 points per game this season (2.6).

Stanford vs SMU Prediction


I’ve bashed Stanford all year, and this is not a good football team. Stanford has lost its way in recent years, no longer tough in the trenches. However, Stanford has had an extra week to prepare, and I love my dogs that have the rest advantage. We’ve also seen Stanford win a game outright this season as a double-digit underdog. Stanford has outright won 2 of its last 5 games as a double-digit underdog. SMU can be spotty defensively and is 0-5 ATS on the season, which includes 0-3 ATS as a double-digit favorite. I’ll take my chances with Stanford and the free points.

Randy Chambers's Pick: Stanford +19.5

Hot Cappers

Latest Picks & Game Previews

  • Philadelphia Eagles vs New York Giants Prediction 10/9/2025 Today’s NFL Picks

    October 09, 2025

  • Utah Hockey Club vs Colorado Avalanche Prediction 10/9/2025 Today’s NHL Picks

    October 09, 2025

  • Brewers vs Cubs Prediction 10/9/2025 Today’s MLB Picks

    October 09, 2025

  • Ducks vs Kraken Prediction 10/9/2025 Today’s NHL Picks

    October 09, 2025

  • Vegas Golden Knights vs San Jose Sharks Prediction 10/9/2025 Today’s NHL Picks

    October 09, 2025

  • Calgary Flames vs Vancouver Canucks Prediction 10/9/2025 Today’s NHL Picks

    October 09, 2025

  • South Florida vs North Texas Prediction 10/10/2025 Today’s College Football Picks

    October 10, 2025

  • Fresno State vs Colorado State Prediction 10/10/2025 Today’s College Football Picks

    October 10, 2025

  • Rutgers vs Washington Prediction 10/10/2025 Today’s College Football Picks

    October 10, 2025

  • Ohio State vs Illinois Prediction 10/11/2025 Today’s College Football Picks

    October 11, 2025