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South Carolina vs Ole Miss Prediction 11/1/2025 Today’s College Football Picks
Pick details
South Carolina (3-5) vs Ole Miss (7-1)
November 1, 2025 at 07:00 PM EDT
The Line: Betting Odds: Ole Miss -12.5 — Over/Under: +54.5
In this article, we will formulate a South Carolina vs Ole Miss Prediction for this College Football Week 10 game on Saturday, November 1st. Let’s take a look at the prediction for this College Football matchup.
Offensively, Ole Miss averages 37.0 points per game, ranking 19th in the nation, while defensively, they allow 23.0 points per game, which is 54th. Ole Miss averages 484.3 total yards per game (305.5 passing and 178.8 rushing), while allowing 361.9 total yards per game (162.9 rushing and 199.0 passing).
Trinidad Chambliss leads Ole Miss with 1,864 passing yards with 61.0% completed passes and 9 touchdowns. Kewan Lacy leads the team in rushing yards with 696, while Harrison Wallace III has a team-high 26 receptions for 464 receiving yards. Defensively, T.J. Dudley has a team-high 52 total tackles (26 of them solo), while Princewill Umanmielen leads the team in sacks, with 3.5. Wydett Williams, Jr., Zxavian Harris and Cedrick Beavers each have one interception.
Offensively, South Carolina averages 20.4 points per game, ranking 117th in the nation, while defensively, they allow 21.1 points per game, which is 39th. South Carolina averages 302.1 total yards per game (195.0 passing and 107.1 rushing), while allowing 335.1 total yards per game (140.6 rushing and 194.5 passing).
LaNorris Sellers leads South Carolina with 1,356 passing yards with 63.2% completed passes and 6 touchdowns. Rahsul Faison leads the team in rushing yards with 298, while Vandrevius Jacobs has a team-high 21 receptions for 343 receiving yards. Defensively, DQ Smith has a team-high 43 total tackles (30 of them solo), while Bryan Thomas Jr. leads the team in sacks, with 5.0, and Gerald Kilgore has a team-high 2 interceptions.
In this South Carolina vs Ole Miss Prediction, Ole Miss is coming as -12.5-point home favorites, with the total set at 54.5 points. Both teams are coming into this matchup in opposite trajectories, as Ole Miss has been almost perfect this season, having lost only once in their seven games played, while on the other hand, South Carolina has three consecutive losses and have been winless on the road. The Rebels have a superior offense, ranking 19th in the league and are scoring almost 17 points per game more than their opponents. Take Ole Miss and lay the -12.5 points in this one.
Ole Miss Rebels Preview
Ole Miss has a 7-1 record this season and is sitting 4th in the SEC. They are 5-3 ATS, 5-3 in Over/Under and have a 5-0 home record and a 2-1 away record. Ole Miss is coming off a 34-26 road win against Oklahoma and will face The Citadel, Florida and Mississippi State next.Offensively, Ole Miss averages 37.0 points per game, ranking 19th in the nation, while defensively, they allow 23.0 points per game, which is 54th. Ole Miss averages 484.3 total yards per game (305.5 passing and 178.8 rushing), while allowing 361.9 total yards per game (162.9 rushing and 199.0 passing).
Trinidad Chambliss leads Ole Miss with 1,864 passing yards with 61.0% completed passes and 9 touchdowns. Kewan Lacy leads the team in rushing yards with 696, while Harrison Wallace III has a team-high 26 receptions for 464 receiving yards. Defensively, T.J. Dudley has a team-high 52 total tackles (26 of them solo), while Princewill Umanmielen leads the team in sacks, with 3.5. Wydett Williams, Jr., Zxavian Harris and Cedrick Beavers each have one interception.
South Carolina Gamecocks Preview
South Carolina has a 3-5 record this season and is sitting 14th in the SEC. They are 4-4 ATS, 3-5 in Over/Under and have a 2-3 home record and a 0-2 away record. South Carolina is coming off a 22-29 home loss against Alabama and will face Texas A&M, Coastal Carolina and Clemson next.Offensively, South Carolina averages 20.4 points per game, ranking 117th in the nation, while defensively, they allow 21.1 points per game, which is 39th. South Carolina averages 302.1 total yards per game (195.0 passing and 107.1 rushing), while allowing 335.1 total yards per game (140.6 rushing and 194.5 passing).
LaNorris Sellers leads South Carolina with 1,356 passing yards with 63.2% completed passes and 6 touchdowns. Rahsul Faison leads the team in rushing yards with 298, while Vandrevius Jacobs has a team-high 21 receptions for 343 receiving yards. Defensively, DQ Smith has a team-high 43 total tackles (30 of them solo), while Bryan Thomas Jr. leads the team in sacks, with 5.0, and Gerald Kilgore has a team-high 2 interceptions.
South Carolina vs Ole Miss Prediction
In their previous meeting last season, Ole Miss won 27-3 on the road, but South Carolina is 3-2 in their 5 meetings and over is 3-2.In this South Carolina vs Ole Miss Prediction, Ole Miss is coming as -12.5-point home favorites, with the total set at 54.5 points. Both teams are coming into this matchup in opposite trajectories, as Ole Miss has been almost perfect this season, having lost only once in their seven games played, while on the other hand, South Carolina has three consecutive losses and have been winless on the road. The Rebels have a superior offense, ranking 19th in the league and are scoring almost 17 points per game more than their opponents. Take Ole Miss and lay the -12.5 points in this one.
