SMU vs Wake Forest Prediction 10/25/2025 Today’s College Football Picks

In this article we will formulate a SMU vs Wake Forest prediction for this College Football game on Saturday, October 25th at Allegacy Federal Credit Union Stadium in Winston-Salem, North Carolina. Let’s take a look at the prediction for this week 9 matchup. 

SMU Mustangs Betting Preview

The SMU Mustangs are 5-2 (3-0) this year after they defeated Clemson by a score of 35-24 in their last game. SMU led 16-7 at halftime and they pulled away in the fourth quarter to get the victory. The Mustangs out gained Clemson by a total of 429-352, went 7-17 on third downs, and tied the turnover battle at one in the game. Kevin Jennings went 23-43 for 290 yards, two touchdowns, and one interception, while Chris Johnson Jr rushed six times for 59 yards and one score. Jordan Hudson led the receivers with seven receptions for 131 yards and one touchdown in the win. The SMU defense recorded four sacks and eight tackles for loss in the game. 

Prior to that win, SMU defeated Stanford by a score of 34-10 and Syracuse by a score of 31-18. The Mustangs have won three games in a row and they are currently tied for second in the ACC standings. SMU has scored 34.1 points per game with 279.6 passing yards and 128.7 rushing yards per game, while they have allowed 22.6 points against per game this season. Kevin Jennings has thrown for 1,948 yards, 17 touchdowns, and seven interceptions, while TJ Harden has rushed for 431 yards and five scores on 96 carries this year. 

Wake Forest Demon Deacons Betting Preview

The Wake Forest Demon Deacons are 4-2 (1-2) this season after they defeated Oregon State by a score of 39-14 in their last game. Wake Forest led 25-0 at halftime and they cruised to the easy win in the second half. The Demon Deacons out gained Oregon State by a total of 468-309, went 1-9 on third downs, and won the turnover battle by a total of 2-0 in the game. Deshawn Purdie went 14-27 for 270 yards and four touchdowns, while Demond Claiborne rushed 16 times for 144 yards and one score. Chris Barnes led the receivers with three catches for 102 yards and three touchdowns in the win. The Wake defense recorded three sacks and three tackles for loss in the game. 

Prior to that game, Wake Forest defeated Virginia Tech by a score of 30-23, but did lose to Georgia Tech by a score of 30-29 before that. The Demon Deacons have won two games in a row and they are currently tied for 11th in the ACC standings. Wake Forest has scored 29.0 points per game with 249.7 passing yards and 160.2 rushing yards per game, while they have allowed 20.0 points against per game this season. Robby Ashford is the starting QB for Wake, but he is dealing with an injury, so we may see Purdie once again. Demond Claiborne has led the rushing attack with 539 yards and eight scores on 69 carries this season. 

Why the SMU Mustangs will win

SMU has won each of its last 10 games in October.
Wake Forest has lost each of its last eight games against conference opponents at Allegacy Federal Credit Union Stadium.
Wake Forest has failed to cover the spread in eight of its last nine home games against non-AP-ranked teams.
SMU has covered the spread in five of its last six road games against conference opponents.

Total Points Facts

Each of Wake Forest’s last four October home games against non-AP-ranked teams have gone UNDER the total points line.
Four of SMU’s last five games have gone UNDER the total points line.

Matchup/League Facts

Wake Forest ranks T4th among FBS teams for Q2 opponent points per game this season (2.2).
Wake Forest ranks T129th among FBS teams for 1st downs this season (109).
SMU ranks T4th among FBS teams for red zone percentage against this season (66.7).
SMU ranks T6th among FBS teams for interceptions this season (10).

SMU vs Wake Forest Prediction 

SMU comes into this matchup with a 3-0 record in conference play and they just got a huge road win against Clemson last week. The Mustangs have scored at least 31 points in three straight games and should take advantage of a weak Wake Forest defense here. The Demon Deacons have won two games in a row, but they have played weaker competition and have allowed 30+ in each of their last two home games. I don’t trust the Wake Forest offense, especially if Ashford is back, so give me SMU on the road. 

David Racey is 80-61 (57%) in College Football this season and is one of the top College Football Handicappers on the site. Click here for his premium plays for the week!