Ole Miss vs Mississippi State Prediction 11/28/2025 Today’s College Football Picks

The Ole Miss Rebels and Mississippi State Bulldogs meet Friday in college football action at Davis Wade Stadium. Here’s a Ole Miss vs Mississippi State Prediction. This article will include a Ole Miss vs Mississippi State Pick.

Ole Miss Rebels Betting Preview

The Ole Miss Rebels beat The Citadel and Florida. The Ole Miss Rebels have won 4 straight games. Trinidad Chambliss is completing 65.2 percent of his passes for 2,657 yards, 14 touchdowns, and 3 interceptions. Harrison Wallace III and Dae’Quan Wright have combined for 1,132 receiving yards and 6 touchdowns, while Deuce Alexander has 32 receptions.

The Ole Miss Rebels ground game is averaging 188.7 yards per contest, and Kewan Lacy leads the way with 1,136 yards and 19 touchdowns. Defensively, Ole Miss is allowing 20.2 points and 323.4 yards per game. TJ Dottery leads the Ole Miss Rebels with 68 tackles, Princewill Umanmielen has 5 sacks and Wydett Williams Jr. has 3 interceptions.

Mississippi State Bulldogs Betting Preview

The Mississippi State Bulldogs lost to Georgia and Missouri. Mississippi State has lost 6 of its last 7 games. Blake Shapen is completing 64.4 percent of his passes for 2,433 yards, 15 touchdowns, and 8 interceptions. Brenen Thompson and Anthony Evans III have combined for 1,619 receiving yards and 10 touchdowns, while Seydou Traore has 30 receptions.

The Mississippi State Bulldogs ground game is averaging 152.5 yards per contest, and Fluff Bothwell leads the way with 559 yards and 6 touchdowns. Defensively, Mississippi State is allowing 28.4 points and 393.2 yards per game. Jahron Manning leads the Mississippi State Bulldogs with 76 tackles, Nic Mitchell has 2.5 sacks and Brylan Lanier has 3 interceptions.

Why the Mississippi State Bulldogs will win

• The underdog has won three of Ole Miss’ last four games at Davis Wade Stadium.
• Ole Miss has failed to cover the spread in 10 of its last 12 November games as a favorite against non-AP-ranked teams.
• Mississippi State has covered the spread in five of its last six home games.

Why the Ole Miss Rebels will win

• Mississippi State has lost each of its last 12 games against conference opponents at Davis Wade Stadium.
• Ole Miss has won each of its last 10 games against non-AP-ranked teams.
• Mississippi State has failed to cover the spread in each of its last six games against top-10 AP-ranked teams at Davis Wade Stadium.
• The road team has covered the spread in three of Ole Miss’ last four games.
• Mississippi State has lost the first half in 10 of its last 12 home games against conference opponents.

Total Points Facts

• Each of the last eight November games between Ole Miss and Mississippi State have gone UNDER the total points line.
• Five of Ole Miss’ last six games as a favorite have gone UNDER the total points line.

Mississippi State Bulldogs Player Prop Facts

• Heading into Week 14, Ethan Pulliam ranks 1st in the Southeastern Conference amongst qualified players for gross average yards per punt (48.1) this season.

Ole Miss Rebels Player Prop Facts

• Heading into Week 14, Kewan Lacy ranks 3rd amongst FBS players for touchdowns (19) this season.

Matchup/League Facts

• Mississippi State ranks T11th among FBS teams for Q1 points per game this season (9.4).
• Mississippi State ranks 14th among FBS teams for average point differential in first quarters this season (+5.5).
• Ole Miss ranks 3rd among FBS teams for yards per game this season (493.8).
• Ole Miss ranks 5th among FBS teams for passing yards per game this season (305.1).

Ole Miss vs Mississippi State Prediction

Ole Miss is the more talented team and clinches a playoff spot with a win. However, there are distractions around Ole Miss with Lane Kiffin possibly leaving the program after the game and while everyone’s saying the right things, it’s an elephant in the room.

Mississippi State isn’t winning games lately, but it’s been in most games and is 8-3 ATS. Mississippi State has covered 7 of its last 11 games as an underdog and is 3-1 ATS this season as a home underdog. The underdog is 6-2-1 ATS in the last nine Egg Bowls. Mississippi State also becomes bowl eligible with a victory and its senior night for 30 seniors. I’ll grab the free touchdown.

Randy Chambers's Pick: Mississippi State +7