Sep 13, 2025; Lexington, Kentucky, USA; Eastern Michigan Eagles running back Dontae McMillan (28) celebrates after running the ball during the second quarter against the Kentucky Wildcats at Kroger Field. Mandatory Credit: Jordan Prather-Imagn Images

Northern Illinois vs Eastern Michigan Prediction 10/11/2025 Today’s College Football Picks

Pick details

Northern Illinois (1-4) vs Eastern Michigan (1-5)

October 11, 2025 at 01:00 PM EDT

The Line: Betting Odds: Eastern Michigan +1 — Over/Under: +46.5

(Get latest betting odds)

The Northern Illinois Huskies and Eastern Michigan Eagles meet Saturday in college football action at Rynearson Stadium. Here’s a Northern Illinois vs Eastern Michigan Prediction. This article will include a Northern Illinois vs Eastern Michigan Pick.

Northern Illinois Huskies Betting Preview


The Northern Illinois Huskies lost to San Diego State and Miami OH, and they play Ohio next. Northern Illinois has lost 4 straight games. Josh Holst is completing 59.7 percent of his passes for 376 yards, 1 touchdown, and 2 interceptions. DeAree Rogers and Telly Johnson Jr. have combined for 313 receiving yards and 1 touchdown, while Gary Givens has 3 receptions.

The Northern Illinois Huskies ground game is averaging 143.8 yards per contest, and Chavon Wright leads the way with 264 yards and 1 touchdown. Defensively, Northern Illinois is allowing 21.2 points and 328.4 yards per game. Quinn Urwiler leads the Northern Illinois Huskies with 64 tackles, Filip Maciorowski has 1.5 sacks and Muhammed Jammeh has 2 interceptions.

Eastern Michigan Eagles Betting Preview


The Eastern Michigan Eagles lost to Kentucky, beat Louisiana, and they play Buffalo next. Eastern Michigan has lost 8 of its last 9 games. Noah Kim is completing 63.1 percent of his passes for 1,336 yards, 7 touchdowns, and 3 interceptions. Terry Lockett Jr. and Nick Devereaux have combined for 489 receiving yards and 2 touchdowns, while Joshua Long has 18 receptions.

The Eastern Michigan Eagles ground game is averaging 154.8 yards per contest, and Dontae McMillan leads the way with 533 yards and 2 touchdowns. Defensively, Eastern Michigan is allowing 35.7 points and 476.7 yards per game. Bryce Liewellyn leads the Eastern Michigan Eagles with 49 tackles, Carter Evans has 1.5 sacks and Caleb Dobbs has 1 interception.

Why the Eastern Michigan Eagles will win

  • Northern Illinois has lost five of its last six October games as a road favorite.
  • The underdog has won each of Eastern Michigan’s last three games at Rynearson Stadium.
  • Northern Illinois has failed to cover the spread in eight of its last nine October games as a favorite.
  • The underdog has covered the spread in each of Eastern Michigan’s last four games at Rynearson Stadium.
  • Northern Illinois has lost the first half in five of its last six road games against conference opponents.

Why the Northern Illinois Huskies will win

  • The favorite has won each of Northern Illinois’ last 10 games.
  • Eastern Michigan has lost each of its last seven games against conference opponents.
  • Northern Illinois has covered the spread in five of its last six games in Michigan.
  • Eastern Michigan has failed to cover the spread in four of its last five games against conference opponents.
  • Northern Illinois has won the first quarter in three of its last four games against conference opponents.
  • Eastern Michigan has lost the first half in four of its last five games against conference opponents.

Total Points Facts

  • Each of Eastern Michigan’s last seven home games against conference opponents have gone OVER the total points line.
  • Each of Northern Illinois’ last five games as a favorite in Michigan have gone OVER the total points line.

Eastern Michigan Eagles Player Prop Facts

  • Heading into Week 7, Dontae McMillan leads the Mid-American Conference for rushing yards (533) this season.

Northern Illinois Huskies Player Prop Facts

  • Heading into Week 7, Muhammed Jammeh leads the Mid-American Conference for interceptions (2) this season.

Matchup/League Facts

  • Eastern Michigan ranks 136th among FBS teams for 1st downs against this season (141).
  • Eastern Michigan ranks T1st among FBS teams for red zone percentage this season (100.0).
  • Northern Illinois has recorded the equal-most home wins by a margin of five points or less of any FBS team this season (1).
  • Northern Illinois has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).

Northern Illinois vs Eastern Michigan Prediction


This is going to be an interesting game because you have possibly the worst offense in the country in Northern Illinois, while Eastern Michigan is one of the worst defenses in the league. It’s trying to figure out which side will bend. While Northern Illinois probably gets the nod because it’s won 8 of the last 10 games against the Eagles, I give Eastern Michigan the edge because of home field. It’s a toss-up between two bad teams so that’s where I look. Northern Illinois has also scored no more than 19 points this season. Yuck. Give me the point with Eastern Michigan at home.

Randy Chambers's Pick: Eastern Michigan +1

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