Nebraska vs Penn State Prediction 11/22/2025 Today’s College Football Picks

In this article we will formulate a Nebraska vs Penn State prediction for this College Football game on Saturday, November 22nd at Beaver Stadium in University Park, Pennsylvania. Let’s take a look at the prediction for this week 13 matchup. 

Nebraska Cornhuskers Betting Preview

The Nebraska Cornhuskers are 7-3 (4-3) this season after they defeated UCLA by a score of 28-21 in their last game. Nebraska led 21-7 at halftime and 28-7 in the third quarter, but barely hung on for the win. The Cornhuskers out gained UCLA by a total of 361-348, went 5-8 on third downs, and tied the turnover battle at one in the game. TJ Lateef went 13-15 for 205 yards and three touchdowns, while Emmett Johnson rushed 28 times for 129 yards and one score. Johnson also led the receivers with three receptions for 103 yards and two touchdowns in the win. The Nebraska defense recorded three sacks and six tackles for loss in the game. 

Prior to that game, Nebraska lost to USC by a score of 21-17, but did beat Northwestern by a score of 28-21 before that. The Cornhuskers have alternated wins and losses over their last five games and they are currently tied for sixth in the Big Ten standings. Nebraska has scored 32.5 points per game with 248.2 passing yards and 137.4 rushing yards per game, while they have allowed 19.9 points against per game this season. TJ Lateef has thrown for 466 yards and four touchdowns, while Emmett Johnson has rushed 203 times for 1,131 yards and 11 scores this season. 

Penn State Nittany Lions Betting Preview

The Penn State Nittany Lions are 4-6 (1-6) this year after they defeated Michigan State by a score of 28-10 in their last game. Penn State led 14-10 at halftime and shutout MSU in the second half for the nice road win. The Nittany Lions out gained Michigan State by a total of 367-229, went 2-10 on third downs, and won the turnover battle by a total of 1-0 in the game. Ethan Grunkemeyer went 8-13 for 127 yards and two touchdowns, while Kaytron Allen rushed 15 times for 181 yards and two scores. Devonte Ross led the receivers with two catches for 79 yards and two touchdowns in the win. The PSU defense recorded five sacks and eight tackles for loss in the game. 

Prior to that game, Penn State lost to Indiana by a score of 27-24 and Ohio State by a score of 38-14. The Nittany Lions have lost six of their last seven games and they are currently tied for 14th in the Big Ten standings. Penn State has scored 29.8 points per game with 178.9 passing yards and 159.9 rushing yards per game, while they have allowed 21.1 points against per game this season. Ethan Grunkemeyer has thrown for 689 yards, four touchdowns, and four interceptions, while Kaytron Allen has rushed 163 times for 917 yards and 12 scores this year. 

Why the Penn State Nittany Lions will win

• Penn State has won 20 of its last 21 home games against non-AP-ranked teams.
• Nebraska has lost 15 of its last 18 road games in November.
• Penn State has covered the spread in 13 of its last 14 November games as a favorite against non-AP-ranked teams.
• Nebraska has failed to cover the spread in four of its last five games against non-AP-ranked teams.

Why the Nebraska Cornhuskers will win

• Penn State has lost three of its last four games as a favorite.
• Penn State has failed to cover the spread in each of its last four home games against non-AP-ranked teams.
• The underdog has covered the spread in five of Nebraska’s last six games.

Total Points Facts

• Nine of Penn State’s last 10 November games at West Shore Home Field at Beaver Stadium have gone UNDER the total points line.
• Seven of Nebraska’s last nine games have gone OVER the total points line.

Matchup/League Facts

• Penn State ranks 12th among FBS teams for average point differential in fourth quarters this season (+4.9).
• Penn State ranks T19th among FBS teams for 1st downs against this season (168).
• Nebraska ranks 3rd among FBS teams for passing yards allowed per game this season (134.6).
• Nebraska ranks 133rd among FBS teams for red zone percentage against this season (95.2).

Nebraska vs Penn State Prediction 

Penn State comes into this matchup after snapping their losing streak with a win over MSU last week and they will be back at home here. The Nittany Lions have played a very difficult schedule since losing their starting quarterback, but they have a solid rushing attack and a strong defense. Nebraska is also without their starting quarterback, but they managed to beat UCLA on the road before their bye week. I think we are going to see both defenses play well and with each team relying on the run, I like the under here.

David Racey is 128-108 (54%) in College Football this season and is one of the top College Football Handicappers on the site. Click here for his premium plays for the week!

David Racey's Pick: Under 44.5