Louisville vs Miami (FL) Prediction 10/17/2025 Today’s College Football Picks

The Louisville Cardinals and the Miami Hurricanes meet in week 8 college football action from Hard Rock Stadium on Friday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Louisville Cardinals vs. Miami Hurricanes prediction.

Louisville Cardinals Recap

The Louisville Cardinals come into this game looking to rebound from a 30-27 loss to Virginia prior to last week’s bye week, falling to 4-1 on the year as a result. After this game, Louisville will head home for a game against Boston College.

Cardinals Looking To Bounce Back From First Loss

Miller Moss has thrown for 1,358 yards, 7 touchdowns and 4 interceptions on 67% passing while Isaac Brown leads Louisville in rushing with 334 rushing yards and 3 touchdowns and Keyjuan Brown has 126 rushing yards and 3 TDs as well. Chris Bell leads Louisville with 35 grabs for 502 receiving yards and 4 touchdowns while Caullin Lacy has 27 catches for 287 yards this season. Two more Louisville receivers have 100+ receiving yards as well this season. On defense, D’Angelo Hutchinson has a team-high 32 total tackles and an interception while Clev Lubin has a team-high 4 sacks. As a unit, Louisville’s defense has combined for 14 sacks and 6 interceptions so far this season.

Miami Hurricanes Recap

The Miami Hurricanes come into this game looking to add on to their 28-22 win over Florida State last time out to sit at 5-0 in their last game prior to last week’s bye week. After this game, Miami will take on Stanford at home.

Hurricanes Looking To Remain Unbeaten

Carson Beck has thrown for 1,213 yards, 11 touchdowns and 3 interceptions on 73.4% passing while Mark Fletcher Jr. has 428 rushing yards and 5 touchdowns on the ground so far this season. CharMar Brown also has 225 rushing yards with 4 scores while Malachi Toney has 29 receptions for 375 yards and a touchdown to lead Miami’s receivers. CJ Daniels has 23 receptions for 269 yards and 5 touchdowns and two more Hurricanes have 100+ receiving yards as well this season. On defense, Rueben Bain Jr. has a team-high 26 total tackles including a pair of sacks while Akheem Mesidor has a team-high 3.5 sacks and Bryce Fitzgerald has a team-high 3 interceptions so far this season. As a unit, Miami’s defense has combined for 12 sacks and 5 interceptions so far this season. 

Louisville Cardinals @ Miami Hurricanes Betting Trends: Week 8

Why the Miami Hurricanes will win

• Miami (FL) has won each of its last 10 games at Hard Rock Stadium.
• Louisville has lost each of its last seven games against top-5 AP-ranked teams.
• Louisville has failed to cover the spread in each of its last five games in October.
• Miami (FL) has covered the spread in five of its last six games at Hard Rock Stadium.
• Miami (FL) has won the first quarter in each of its last seven games against conference opponents.
• Miami (FL) has won the first half in each of its last three games against conference opponents.

Why the Louisville Cardinals will win

• Louisville has won each of its last three games as an underdog in Florida.
• Miami (FL) has failed to cover the spread in each of its last 13 October games as a home favorite against non-AP-ranked teams.
• The underdog has covered the spread in five of Louisville’s last six games.

Total Points Facts

• Each of the last four games between Louisville and Miami (FL) have gone OVER the total points line.
• Four of Louisville’s last five games as an underdog have gone OVER the total points line.

Miami Hurricanes Player Prop Facts

• Heading into Week 8, Bryce Fitzgerald ranks T6th amongst FBS players for interceptions (3) this season.

Louisville Cardinals Player Prop Facts

• Chris Bell has recorded 50+ receiving yards in nine consecutive games – equal-longest streak in the FBS, heading into Week 8.

Matchup/League Facts

• Miami (FL) has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
• Miami (FL) ranks 3rd among FBS teams for H1 opponent points per game this season (3.8).
• Louisville ranks 3rd among FBS teams for 1st downs against this season (71).
• Louisville ranks 8th among FBS teams for passing yards allowed per game this season (150.4).

Louisville Cardinals vs. Miami Hurricanes Prediction

I’m leaning towards Louisville and the points here. I just think this is a case of too many points here and while I do think Miami wins this game, I think Louisville is going to be up to the task here. Miami kind of left the backdoor open against Florida State, and I think Louisville could be live in this game. Give me the Cardinals and the points in this one.