James Madison vs Oregon Prediction 12/20/2025 Today’s College Football Picks

The James Madison Dukes and Oregon Ducks meet Saturday in the College Football Playoff at Autzen Stadium. Here’s a James Madison vs Oregon Prediction. This article will include a James Madison vs Oregon Pick.

James Madison Dukes Betting Preview

The James Madison Dukes beat Troy and Coastal Carolina. The James Madison Dukes have won 11 straight games. Alonza Barnett III is completing 59.9 percent of his passes for 2,533 yards, 21 touchdowns, and 8 interceptions. Landon Ellis and Nick DeGennaro have combined for 951 receiving yards and 9 touchdowns, while Wayne Knight has 37 receptions.

The James Madison Dukes ground game is averaging 245.8 yards per contest, and Wayne Knight leads the way with 1,263 yards and 9 touchdowns. Defensively, James Madison is allowing 15.8 points and 247.6 yards per game. Trent Hendrick leads the James Madison Dukes with 96 tackles, Sahir West has 7 sacks and Justin Eaglin has 4 interceptions.

Oregon Ducks Betting Preview

The Oregon Ducks beat Washington and USC. Oregon has won 6 straight games. Dante Moore is completing 72.5 percent of his passes for 2,733 yards, 24 touchdowns, and 6 interceptions. Kenyon Sadiq and Malik Benson have combined for 1,016 receiving yards and 12 touchdowns, while Dakorien Moore has 28 receptions.

The Oregon Ducks ground game is averaging 238.3 yards per contest, and Noah Whittington leads the way with 774 yards and 6 touchdowns. Defensively, Oregon is allowing 16.2 points and 274.5 yards per game. Bryce Boettcher leads the Oregon Ducks with 104 tackles, Teitum Tuioti has 7 sacks and Jerry Mixon has 2 interceptions.

James Madison vs Oregon Prediction

You can talk yourself into the points with James Madison. The Dukes have won 11 straight games and on paper are arguably the best team in the country. James Madison is 11th in scoring offense, second in total defense and ninth in scoring defense. James Madison is also a winning program that’s been a double-digit underdog just four times previously since 2016. Last year, James Madison beat North Carolina as a double-digit underdog. With all of that said, James Madison hasn’t played anybody this season and its toughest opponent was Louisville, which it lost by two touchdowns in week 2. A trip to Autzen Stadium is a completely different beast.

Oregon is 7-2 ATS in its last 9 games as a double-digit favorite. Oregon is 6-3 ATS in its last 9 games as favorites of 20 or more points. Against great competition, Oregon is sixth in scoring offense and 11th in scoring defense. We know what Oregon can do. James Madison is a bit of a mystery. We’ll learn a lot more about James Madison in this game. Until questions are answered, I’m going to lay the points with the Ducks.

Randy Chambers's Pick: Oregon -21