James Madison vs Liberty Prediction 9/20/2025 Today’s College Football Picks

James Madison and Liberty meet Saturday in Week 4 college football action from Williams Stadium. Here’s a James Madison vs Liberty prediction. We will look at this from a betting perspective and determine the best James Madison Dukes vs Liberty Flames pick. We will examine:

The James Madison Dukes’ recent form and player performance

The Liberty Flames’ recent form and player performance

Recent betting trends and streaks involving the Flames

Recent betting trends and streaks involving the Dukes

Recent betting trends in games played between James Madison and Liberty

A summary that ties it all together and produces a favorable betting outcome for the James Madison and Liberty game.

Was the Bye Week Good for James Madison?

In the first game of the season, James Madison was able to knock off Weber State 45-10. In the last game against Louisville, they were competitive, but they blew it in the second half and that they ended up losing 28-14. In the 4th quarter, they were outscored 14-0. James Madison had only 263 yards of total offense, but they allowed Louisville to put up 264 total yards. Alonzo Barnett III completed 15 of his 25 passes for 102 yards, one touchdown, and zero interceptions. Matthew Sulka was the top rusher finishing with 21 carries for 83 yards and a touchdown. In the first game they picked off Weber State three times, and creating some turnovers is going to be a big time key here. 

James Madison on the season is averaging 29.5 points while their defense is giving up 19 points per game. The offense is ranked 71st in all of college football while the defense is ranked 53rd. There are no reported injuries for James Madison heading into this game. 

Why James Madison Will Beat Liberty

James Madison has won 11 of its last 12 September games against non-AP-ranked teams.
Liberty has lost four of its last five games against non-AP-ranked teams.
Liberty has failed to cover the spread in each of its last five games.
James Madison has covered the spread in each of its last four road games in September.

Slow Start for Liberty

Liberty lost a whole lot in the transfer portal, so it’s not all that shocking it’s been a slow start to the season. In the first game of the season, Liberty was able to beat Maine 28-7, but since that point they have lost two straight games. Two games ago against Jacksonville State they lost 34-24, and in the last game against Bowling Green, they lost 23-13. They didn’t score any points in the first half, and that led to the defeat. Ethan Vasko was under center and he completed 13 of his 24 passes 194 yards, one touchdown, and two interceptions. He can’t be turning the ball over if they want to find success. 

Liberty is averaging 21.67 points while their defense is giving up 21.33 points per game. The offense is ranked 100th while the defense is ranked 68th. Turnovers are going to be the biggest key for Liberty in this game. 

Why Liberty Will Beat James Madison

Liberty has won each of its last 12 September games at Arthur L. Williams Stadium.
James Madison has lost four of its last five road games.
Liberty has covered the spread in each of its last four September games as an underdog.

James Madison vs Liberty Prediction

This is one of the most the games I am most excited about this weekend because we are going to find out a lot about both of the teams. I still believe this James Madison team could be a college football playoff team, or at least in the conversation late in the season, and they are going to make a quite statement in this game. James Madison’s defense is giving up 19 points per game, and they are going to create a few turnovers here. Liberty has had turnovers, and they are going to give them a couple of them away here. James Madison will get good quarterback play again from Barnett III, and it’s going be the Dukes that are going to cruise here. Back James Madison against the spread.