Oct 18, 2025; Bloomington, Indiana, USA; Indiana Hoosiers quarterback Fernando Mendoza (15) throws a pass during the first half against the Michigan State Spartans at Memorial Stadium. Mandatory Credit: Robert Goddin-Imagn Images
Robert Goddin-Imagn Images

Indiana vs Maryland Prediction 11/1/2025 Today’s College Football Picks

Pick details

Indiana (8-0) vs Maryland (4-3)

November 1, 2025 at 03:30 PM EDT

The Line: Betting Odds: Maryland +21 — Over/Under: +50.5

(Get latest betting odds)

The Indiana Hoosiers and the Maryland Terrapins meet in week 10 college football action from SECU Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Indiana Hoosiers vs. Maryland Terrapins prediction.

Indiana Hoosiers Recap

The Indiana Hoosiers come into this game looking to add on to their 56-6 win over UCLA last time out to sit at 8-0 this season. After this game, Indiana will head on the road for a game against Penn State.

Hoosiers Looking To Remain Unbeaten

Fernando Mendoza leads Indiana in passing with 1,923 yards, 24 touchdowns and 3 interceptions on 72.9% passing while Roman Hemby has 513 rushing yards with 4 TDs while Kaelon Black has 509 rushing yards with 3 TDs. Elijah Sarratt leads Indiana with 45 catches for 609 yards and 10 touchdowns while Omar Cooper Jr. has 39 catches for 583 yards and 7 TDs. E.J. Williams Jr. also has 321 receiving yards and 5 TDs. On defense, Louis Moore has a team-high 55 total tackles along with 4 interceptions while Isaiah Jones and Rolijah Hardy each have a team-high 5 sacks. As a unit, Indiana’s defense has combined for 29 sacks and 11 interceptions so far this season.

Maryland Terrapins Recap

The Maryland Terrapins come into this game looking to rebound from a 20-17 loss at the hands of UCLA last time out to sit at 4-3 this season. After this game, Maryland will head on the road for a game against Rutgers.

Terrapins Drop 3 In A Row

Malik Washington has thrown for 1,716 yards, 11 touchdowns and 3 interceptions on 59.7% passing to lead Maryland while DeJuan Williams has 292 rushing yards and 2 touchdowns this season on the ground. Shaleak Knotts has a team-high 421 receiving yards and 5 TDs while Octavian Smith Jr. has 378 receiving yards and Jalil Farooq has a team-high 31 catches for 277 yards this season. On defense, Daniel Wingate has a team-high 65 total tackles while Sidney Stewart leads the Terrapins with 5.5 sacks and Zahir Mathis has 4.5 sacks. Jalen Huskey leads Maryland with 3 INTs while Maryland’s defense has combined for 22 sacks and 14 interceptions so far this season.

Indiana Hoosiers @ Maryland Terrapins Betting Trends: Week 10

Why the Maryland Terrapins will win

  • The home team has won 10 of Indiana’s last 12 games.
  • Indiana has lost seven of its last nine road games in November.
  • The underdog has covered the spread in each of Maryland’s last six games.
  • The team ranked 2nd in the AP Poll has failed to cover the spread in six of its last seven games.

Why the Indiana Hoosiers will win

  • Indiana has won each of its last 17 games against non-AP-ranked teams.
  • Maryland has lost 18 of its last 19 games against AP-ranked teams.
  • Indiana has covered the spread in each of its last four November road games against non-AP-ranked teams.
  • Maryland has failed to cover the spread in five of its last six games against teams from Indiana.
  • Maryland has lost the first half in eight of its last nine home games against conference opponents.
  • Indiana has won the first quarter in each of its last eight games against conference opponents.

Total Points Facts

  • Each of Indiana’s last seven road games in November have gone OVER the total points line.
  • Twelve of Maryland’s last 13 games against teams from Indiana have gone OVER the total points line.

Maryland Terrapins Player Prop Facts

  • Heading into Week 10, Malik Washington ranks 1st amongst qualified players for sack percentage (0.7%) this season.

Indiana Hoosiers Player Prop Facts

  • Heading into Week 10, Elijah Sarratt ranks 1st amongst FBS players for receiving touchdowns (10) this season.

Matchup/League Facts

  • Maryland ranks 2nd among FBS teams for interceptions this season (14).
  • Maryland ranks 5th among FBS teams for average point differential in second quarters this season (+8.4).
  • Indiana has recorded the most home wins by a margin of 10+ points of any FBS team this season (6).
  • Indiana has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (5).

Indiana Hoosiers vs. Maryland Terrapins Prediction

I’m on the Hoosiers here. If Penn State was what they were expected to be this season, maybe I could make a case about a lookahead spot. However, Indiana’s a machine right now, and are showing no signs of slowing up, while Maryland has taken three straight close losses against teams nowhere near what they’re up against in this game. I think this is going to be a rough one for the Terps, who had so much promise coming into conference play as I think the Hoosiers roll here. Give me Indiana.

Chris Ruffolo's Pick: Indiana -21

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