Duke vs Middle Tennessee Prediction College Football Picks 9/21/24

Pick details

Middle Tennessee (1-2) vs Duke (3-0)

September 21, 2024 at 04:00 PM EDT

The Line: Betting Odds: Middle Tennessee +14.5 — Over/Under: 54

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In this article, we will formulate a Duke vs Middle Tennessee prediction for this College Football Week 4 game on Saturday, September 21st, at Floyd Stadium.  Let’s take a look at a Duke Blue Devils vs Middle Tennessee Blue Raiders pick. To formulate this prediction, we will examine:

-The Blue Devils’ recent form and recent player performance 

-The Blue Raiders’ recent form and recent player performance

-Recent Betting trends and streaks involving Duke

-Recent Betting trends and streaks involving Middle Tennessee

-Recent betting trends in games played between Duke and Middle Tennessee

-A summary that ties it all together and produces a favorable betting outcome for Today’s Game between the Blue Devils and Blue Raiders. 

Duke Have Been Consistent

The Duke has been consistent to start the season and in each of the three games they have scored 26 points. Two games ago against Northwestern, it took overtime, but Duke was able to secure the 26-20 victory. In the last game against UConn, they weren’t dominant but they were able to secure the 26-21 victory. Maalik Murphy had a huge game completing 28 of his 43 passes for 267 yards, three touchdowns, and one interception. Running back Starr Thomas also had a huge game finishing with 22 carries for 122 yards. Sean Brown finished with 11 catches for 87 yards and a touchdown. In this game, Duke needs the defense to step up in a big way here. 

Why Duke Will Beat Middle Tennessee

  • Duke has won each of its last eight September games as a favorite.
  • Middle Tennessee has lost each of its last seven games as an underdog.
  • Middle Tennessee has failed to cover the spread in each of its last five games.
  • Duke has covered the spread in 10 of its last 13 September road games against non-AP-ranked teams.

Middle Tennessee Has Lost Two Straight Games


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Middle Tennessee has lost two straight games and they are struggling heading into this one. Two games ago against Ole Miss, Middle Tennessee only scored three points while the defense gave up 52 points. In the last game against Western Kentucky, the offense was better, but they still weren’t good enough. Middle Tennessee scored 21 points but the defense gave up 49 points. Even though the defense was awful, the offense actually was decent with the moving ball. Under center for Middle Tennessee is Nicolas Vattiato and he completed 24 of his 31 passes for 456 yards, three touchdowns, and one interception. If they are going to find success in this game they are going to need the defense to be better here. 

Duke vs Middle Tennessee Prediction

Duke has been consistently scoring 26 points, but in this game, they are going to go even higher than that. This Middle Tennessee defense is garbage and their garbage defense is going to be a problem again here. Duke is going to have no issue running up the score here, and the Middle Tennesse is going to have no issue getting the job done here. Back Duke to win this game and cover the spread. 

Shane Mickle's Pick: Duke -14.5

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