Charlotte vs Indiana Prediction College Football Picks 9/21/24

Pick details

Indiana (3-0) vs Charlotte (1-2)

September 21, 2024 at 12:00 PM EDT

The Line: Betting Odds: Indiana -28.5 / Charlotte +28.5 — Over/Under: 51

(Get latest betting odds)

The Charlotte 49ers and the Indiana Hoosiers meet in week 4 college football action from Memorial Stadium on Saturday afternoon. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Charlotte vs. Indiana prediction.

Charlotte Recap

The Charlotte 49ers come into this one looking to build on their first win of the season after a 27-26 win over Gardner-Webb last time out to climb to 1-2 on the year. After this game, Charlotte will stay on the road and take on Rice in their conference opener.

49ers Still Struggling With Injuries

Max Brown has thrown for 368 yards, a touchdown, and 2 interceptions on 52.6% passing while Deshawn Purdie has 328 passing yards, 2 touchdowns, and an interception on 59.5% passing and Trexler Ivey has 142 passing yards and 2 TDs on 91.7% passing. Hahsaun Wilson has a team-high 116 rushing yards and a touchdown while Jairus Mack has a team-high 157 receiving yards. Colin Weber also has a team-high 14 grabs for 143 yards while Sean Brown and Bryce Kennon each have 100+ receiving yards as well on the year. On defense, Reid Williford has a team-high 19 total tackles with 10 solo tackles while Al-Ma’hi Ali has 16 total tackles including a team-high 11 solo tackles and a pair of interceptions. Stephen Sings V also has a team-high 2 sacks for Charlotte. As a unit, Charlotte’s defense has combined for 8 sacks and 5 interceptions this season.

Why the Charlotte 49ers will win

  • The road team has covered the spread in 13 of Charlotte’s last 15 games.

Indiana Recap

The Indiana Hoosiers come into this one looking to remain unbeaten after picking up a huge 42-13 win over UCLA last time out to improve to 3-0 on the year. After this game, Indiana goes home to welcome Maryland to town.

Hoosiers Rolling Offensively

Kurtis Rourke has thrown for 755 yards and 7 touchdowns on 74.3% passing while Justice Ellison has 232 rushing yards and 3 touchdowns while Ty’Son Lawton has 149 rushing yards with 3 TDs and Elijah Green has 128 rushing yards with 3 TDs as well. Omar Cooper Jr. has a team-high 234 receiving yards with 2 touchdown grabs while Elijah Sarratt has a team-high 12 receptions for 203 yards and Miles Cross and Myles Price each have 100+ receiving yards on the year as well. On defense, Aiden Fisher has a team-high 30 total tackles including 11 solo tackles while Mikail Kamara has a team-high 3 sacks and Amare Ferrell has a pair of interceptions. As a unit, Indiana has combined for 12 sacks and 4 interceptions.

Why the Indiana Hoosiers will win

  • Charlotte has lost 17 of its last 18 road games against non-conference opponents.
  • Indiana has won each of its last 17 September games as a favorite.
  • Charlotte has failed to cover the spread in four of its last five games.
  • Indiana has covered the spread in six of its last eight games.

Charlotte vs. Indiana Prediction

I’m going to lay the big number with Indiana here. The Hoosiers just look like a different animal with Curt Cignetti leading the charge and Cignetti’s brought his ideology from James Madison and the winning mentality that went on with the Dukes and translated that within this Hoosiers program. The 49ers just don’t have the healthy pieces to contend here and I think that Indiana rips off another massive win here. Give me the Hoosiers in a landslide.

Chris Ruffolo's Pick: Indiana -28.5

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