Sep 20, 2025; Louisville, Kentucky, USA;  Louisville Cardinals wide receiver Caullin Lacy (5) is defended by Bowling Green Falcons cornerback MJ Cannon (2) during the second half at L&N Federal Credit Union Stadium. Louisville defeated Bowling Green 40-17. Mandatory Credit: Jamie Rhodes-Imagn Images

Bowling Green vs Ohio Prediction 9/27/2025 Today’s College Football Picks

Pick details

Bowling Green (2-2) vs Ohio (2-2)

September 27, 2025 at 12:00 PM EDT

The Line: Betting Odds: Ohio -10 — Over/Under: 50.5

(Get latest betting odds)

Bowling Green and Ohio meet Saturday in Week 5 college football action from Peden Stadium. Here’s a Bowling Green vs Ohio prediction. We will look at this from a betting perspective and determine the best Bowling Green Falcons vs Ohio Bobcats pick. We will examine:

The Bowling Green Falcons’ recent form and player performance
The Ohio Bobcats’ recent form and player performance
Recent betting trends and streaks involving the Falcons
Recent betting trends and streaks involving the Bobcats 
Recent betting trends in games played between Bowling Green and Ohio
A summary that ties it all together and produces a favorable betting outcome for the Bowling Green vs Ohio game.

Bowling Green Has Been Tested


Bowling Green has been tested to start the season, and this is a team that could find a lot of success in the MAC. Bowling Green sits with a 2-1 record and that includes a 23-13 victory over Liberty. In the last game against Louisville, Bowling Green scored 17 points but the defense really let them down, giving up 40 points. The two touchdowns for Bowling Green were also scored in the 4th quarter so the score looked a little closer than it actually was. Drew Payne is under center for Bowling Green, and he completed 11 of his 21 of his passes for 131 yards, one touchdown, and two interceptions. 

Bowling Green on the season is averaging 21.5 points while their defense is giving up 23.5 points per game. The offense is ranked 104th in all of college football while the defense is 73rd. Pyne on the season has completed 64.2 percent of his passes for 660 yards, three touchdowns, and two interceptions. 

Ohio Looks Good


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Ohio looks good, don’t be fooled by their 2-2 record, Ohio looks like they could be one of the best teams in the MAC. Three games ago against West Virginia, Ohio was able to secure the 17-10 victory. The two losses for Ohio came against Rutgers by three points, and 37-9 against Ohio State. In the last game against Gardner Webb, Ohio State scored 52 points and even though the defense had some holes, it was still quite impressive. Parker Navarro completed 18 of his 27 passes for 290 yards, one touchdown, and zero interceptions. The running game went wild though. Sieh Bangura finished with 18 carries for 123 yards, and three touchdowns. Duncan Brune also rushed 16 times for 88 yards and three touchdowns. 

Ohio on the season, is averaging 27.3 points while their defense is giving up 29 points per game. The offense is ranked 82nd in college football while the defense is ranked 105th. Ohio’s offense has to get out to a fast start here. 

Matchup/League Facts

  • Ohio ranks T120th among FBS teams for Q4 points per game this season (3.5).
  • Ohio ranks 118th among FBS teams for yards allowed per game this season (425.3).
  • Bowling Green ranks 121st among FBS teams for H1 points per game this season (8.3).
  • Bowling Green ranks 119th among FBS teams for yards per game this season (315.8).

Bowling Green vs Ohio Prediction


Is Ohio going to win this game? Yes I expect they are, but this also feels like just too many points. Bowling Green should have a lot of confidence with how they played in non-conference, and I trust their quarterback. Drew Payne has been strong to start the season, and now that he’s not playing the Ohio State’s of the world, I expect him to be even better. He’s going to throw for a couple of touchdowns, not throw any interceptions, and Bowling Green is going to keep it within a touchdown. Back Bowling Green against the spread.

Shane Mickle's Pick: Bowling Green +10

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