Arizona State vs Iowa State Prediction 11/1/2025 Today’s College Football Picks

In this article, we will formulate an Arizona State vs Iowa State Prediction for this College Football Week 10 game on Saturday, November 1st. Let’s take a look at the prediction for this College Football matchup.

Iowa State Cyclones Preview

Iowa State has a 5-3 record this season and is sitting 6th in the Big 12. They are 3-4 ATS, 4-4 in Over/Under and have a 3-1 home record and a 1-2 away record. Iowa State is coming off a 27-41 home loss against BYU and will face Texas Christian, Kansas and Oklahoma State next.

Offensively, Iowa State averages 29.0 points per game, ranking 67th in the nation, while defensively, they allow 21.8 points per game, which is 45th. Iowa State averages 417.1 total yards per game (250.8 passing and 166.4 rushing), while allowing 353.4 total yards per game (136.8 rushing and 216.6 passing).

Rocco Becht leads Iowa State with 1,933 passing yards with 63.7% completed passes and 10 touchdowns. Abu Sama leads the team in rushing yards with 544, while Brett Eskildsen has a team-high 29 receptions for 409 receiving yards. Defensively, Marcus Neal has a team-high 54 total tackles (31 of them solo), while Will McLaughlin leads the team in sacks, with 2.0, and Jamison Patton has a team-high 2 interceptions.

Arizona State Sun Devils Preview

Arizona State has a 5-3 record this season and is sitting 3rd in the Big 12. They are 4-4 ATS, 2-6 in Over/Under and have a 4-1 home record and a 1-2 away record. Arizona State is coming off a 16-24 home loss against Houston and will face West Virginia, Colorado and Arizona next.

Offensively, Arizona State averages 26.0 points per game, ranking 79th in the nation, while defensively, they allow 27.7 points per game, which is 88th. Arizona State averages 401.1 total yards per game (226.3 passing and 174.9 rushing), while allowing 334.6 total yards per game (119.9 rushing and 214.8 passing).

Sam Leavitt leads Arizona State with 1,628 passing yards with 60.7% completed passes and 10 touchdowns. Raleek Brown leads the team in rushing yards with 706, while Jordyn Tyson has a team-high 57 receptions for 628 receiving yards. Defensively, Keyshaun Elliot has a team-high 67 total tackles (35 of them solo), while Prince Dorbah leads the team in sacks, with 4.0, and Martell Hughes has a team-high 2 interceptions.

Arizona State vs Iowa State Prediction

In their previous meeting last season, Arizona State won 45-19 at home, covering the spread as the game went over the point total. 

In this Arizona State vs Iowa State Prediction, Iowa State is coming as -5.5-point home favorites, with the total set at 50.5 points. Both teams have identical records this season and both are struggling coming into this matchup, as Iowa State has lost three straight and Arizona State is 1-2 in its last three. Iowa State has been almost perfect at home with a 3-1 record and are better than Arizona State both offensively and defensively, winning by an average of 7.2 points per game. Take the better team playing at home to win this one. Take Iowa State and lay the -5.5 points.