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Alabama vs Missouri Prediction 10/11/2025 Today’s College Football Picks
Pick details
Alabama (4-1) vs Missouri (5-0)
October 11, 2025 at 12:00 PM EDT
The Line: Betting Odds: Missouri +3 — Over/Under: +51.5
In this article, we will formulate an Alabama vs Missouri Prediction for this College Football Week 7 game on Saturday, October 11th at the Memorial Stadium. Let’s take a look at the prediction for this College Football matchup.
Missouri Tigers Preview
The Missouri Tigers have a 5-0 record this season and are sitting on the 1st place of the SEC. They are 3-2 ATS, 4-1 in Over/Under and have a 5-0 home record. The Tigers are coming off a 42-6 home win against Massachusetts and are playing Auburn and Vanderbilt next.
Offensively, the Tigers average 45.2 points per game, which ranks 7th in the nation. Defensively, they allow 14.6 points per game, which is 16th. Missouri averages 547.6 total yards per game, with 292 rushing yards and 255.6 passing yards per game. They allow 203.8 total yards per game, with 62.4 rushing and 141.4 passing yards per game.
Beau Pribula leads the Tigers with 1203 passing yards and 75.9% completed passes. Ahmad Hardy leads the team in rushing yards, with 730, while Marquis Johnson has a team-high 18 caught passes for 275 receiving yards, and two touchdowns. Defensively, Josiah Trotter has a team-high 28 total tackles, 14 of them solo. Damon Wilson II leads the Tigers in sacks, with 3.5, while Nicholas Rodriguez has one interception.
Alabama Crimson Tide Preview
The Alabama Crimson Tide have a 4-1 record this season and are sitting on the 7th place of the SEC. They are 4-1 ATS, 3-2 in Over/Under and have a 1-1 away record and 3-0 home record. The Crimson Tide are coming off a 30-14 home win against Vanderbilt and are playing Tennessee and South Carolina next.
Offensively, the Crimson Tide average 36.4 points per game, which ranks 31st in the nation. Defensively, they allow 16 points per game, which is 21st. Alabama averages 452.2 total yards per game, with 126.8 rushing yards and 325.4 passing yards per game. They allow 285.8 total yards per game, with 155.4 rushing and 130.4 passing yards per game.
Ty Simpson leads the Crimson Tide with 1478 passing yards and 70.3% completed passes. Jamarion Miller leads the team in rushing yards, with 182, while Cole Adams has a team-high 25 caught passes for 392 receiving yards, and one touchdown. Defensively, Justin Jefferson has a team-high 35 total tackles, 19 of them solo. Lebbeus Overton leads the Crimson Tide in sacks, with 1.5, while Bray Hubbard has two interceptions.
Alabama Crimson Tide @ Missouri Tigers Betting Trends: Week 7
Why the Missouri Tigers will win
- Missouri has won each of its last 15 games at Faurot Field at Memorial Stadium.
- The team ranked 8th in the AP Poll has lost six of its last eight games.
- The team ranked 8th in the AP Poll has failed to cover the spread in eight of its last nine games.
- Missouri has covered the spread in eight of its last 10 games.
Why the Alabama Crimson Tide will win
- The favorite has won each of Missouri’s last nine games.
- Missouri has lost each of its last eight October games against top-15 AP-ranked teams.
- Alabama has covered the spread in 15 of its last 17 October games against AP-ranked teams.
- Missouri has failed to cover the spread in four of its last five October games against top-15 AP-ranked teams.
- Alabama has won the first half in 10 of its last 13 games against conference opponents.
- Alabama has won the first quarter in five of its last six games against conference opponents.
Total Points Facts
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- Each of Alabama’s last seven games against conference opponents have gone UNDER the total points line.
- Seven of Missouri’s last eight October games against top-15 AP-ranked teams have gone UNDER the total points line.
Missouri Tigers Player Prop Facts
- Heading into Week 7, Ahmad Hardy ranks 1st amongst FBS players for rushing yards (730) this season.
Alabama Crimson Tide Player Prop Facts
- Heading into Week 7, Bray Hubbard leads the Southeastern Conference for interceptions (2) this season.
Matchup/League Facts
- Missouri has recorded the equal-most home wins by a margin of 10+ points of any FBS team this season (4).
- Missouri has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (3).
- Alabama has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (3).
- Alabama ranks 5th among FBS teams for passing yards per game this season (325.4).
Alabama vs Missouri Prediction
In their previous meeting last season, Alabama won 34-0 at home, and have won all five meetings against Missouri, and are 4-1 against the spread. Over is 3-2 in their five meetings.
In this Alabama vs Missouri Prediction, Alabama is coming as -3-point road favorites, with the total set at 51.5 points. Both teams have been outstanding this season, with Missouri being undefeated, and Alabama having lost only once. Missouri is playing its sixth straight home game, while Alabama is 1-1 on the road. The Tigers are better both offensively and defensively, and are winning by an average of 30.6 points per game this season. I like the hosts as home dogs in this spot, so take Missouri and the +3 points in this one.