Peyton Stearns, of the United States, returns to Anna Kalinskaya, of Russia, during the Cincinnati Open at the Lindner Family Tennis Center in Mason, Ohio, on Aug. 9, 2025.
Albert Cesare/The Enquirer / USA TODAY NETWORK via Imagn Images

WTA Madrid: Peyton Stearns vs Lois Boisson Prediction 4/21/2026 Today’s Tennis Picks

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Madrid Open Prediction: Peyton Stearns vs Lois Boisson

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The Line: Betting Odds: Peyton Stearns / Lois Boisson (TBC)

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Peyton Stearns faces Lois Boisson in the first round of the 2026 Madrid Open. The match is scheduled for Tuesday, April 21. Here’s our Peyton Stearns vs Lois Boisson prediction. This preview will also include a Peyton Stearns vs Lois Boisson pick.

Peyton Stearns vs Lois Boisson Preview

Peyton Stearns enters the 2026 Madrid Open ranked 43rd in the WTA rankings. This will be her third appearance in this tournament. She lost in the first round to Tatjana Maria in 2024, but made the last 16 in 2025 with three victories before bowing out at the hands of eventual champion Aryna Sabalenka.

Stearns has one clay-court title to her name – a WTA 250 she won in Rabat, Morocco, a couple of seasons ago. It was her first tour-level title. Stearns began her clay-court swing on home soil in Charleston, where she lost in the last 16 to McCartney Kessler in three sets. Overall, Stearns has compiled 12 wins and 9 losses in 2026.

Lois Boisson enters the 2026 Madrid Open ranked 44th in the WTA rankings. This will be her debut appearance at the event. Boisson made waves when she made the semifinals of the 2025 French Open at home as a wild card. That breakthrough run in Paris helped Boisson reach the world’s Top 50 and up to a career high of World No. 34. 

But since retiring from her match in Beijing at the end of September 2025, Boisson has not played a single minute of competitive tennis because of persistent injuries. She withdrew from a handful of tournaments in the first quarter of 2026, including the Australian Open, Indian Wells, and Miami. The Frenchwoman recently noted that her injury problems are finally behind and will launch her comeback in Madrid. 

Peyton Stearns vs Lois Boisson Head-To-Head

Stearns and Boisson have never played at the WTA level, so this will be their first career meeting. Whoever wins this match will earn a second round showdown against World No. 1 Aryna Sabalenka.

Peyton Stearns vs Lois Boisson Prediction

This would have been a tricky match for Stearns had Boisson been fit, but the Frenchwoman has not played a single minute of competitive tennis since September 2025 due to injuries. It’s asking a lot of Boisson to get a result right off the bat in her first tournament of 2026. I expect Stearns to dominate the points with her massive forehand and secure a comfortable victory.

Nur Said's Pick: Stearns in straight sets

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