Vienna Prediction: Popyrin vs Berrettini 10/21/2025 Today’s Tennis Picks

Alexei Popyrin will face former Top 10 player Matteo Berrettini in the first round of the 2025 Vienna Open on Tuesday, October 20. Here’s our Alexei Popyrin vs Matteo Berretini prediction. This preview will also include an Alexei Popyrin vs Matteo Berretini pick.

Alexei Popyrin vs Matteo Berretini Preview

Alexei Popyrin is ranked 48th in the ATP rankings, having fallen from a career high of No. 19. Popyrin’s big goal before the season ends will be to retain a top 50 spot. The Australian has won 18 matches and lost 22 times and saw his title defense at the Canada Masters come to an end in the quarterfinal stage.

Popyrin has since won two matches in the last three tournaments and is coming off a first-round exit in Stockholm, where he lost to Sebastian Korda in three sets. That was Popyrin’s first match since recovering from a back injury that ruled him out of action for the whole of September. Popyrin has featured in three main draws at the Vienna Open, but the 26-year-old has yet to get off the mark in Austria’s capital, losing in the first round each time.

If that is to change, Popyrin will need to beat Matteo Berrettini, who has a decent track record in this tournament. Berrettini has made the semifinals once in Vienna and was a quarterfinalist in each of his last two visits and played one of the classic matches at the event in a three-set defeat to Carlos Alcaraz in 2021.

Berrettini has endured another frustrating season with injuries and the Italian finds himself in 61st position in the ATP rankings. He has played 31 matches in 2025 and has compiled a 16-15 record. His best results were on hard courts earlier this year when he made quarterfinals in Doha, Dubai, and Miami. Berrettini won three tournaments last year, but hasn’t quite made similar runs this season.

Alexei Popyrin vs Matteo Berretini Head-To-Head

Popyrin and Berrettini have met three times on the ATP level. Berrettini leads Popyrin 2-1 in the head-to-head and won their meeting at the 2021 Vienna Open in straight sets.

Alexei Popyrin vs Matteo Berretini Prediction

It’s not a matchup where I have so much confidence picking the winner outright. These are indoor conditions, and it should be a match of fine margins with both players being massive hitters, and momentum hinging on a few crucial points. But with Berrettini having a more structured game with patterns and variety to switch up things, I’d probably just lean toward him to win this. He has also not lost before the quarterfinals in Vienna, so he loves playing in this tournament.