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Manchester United vs Brentford 9/27/25 Prediction English Premier League Picks

Pick details

Brentford 1-3-1 – Manchester United 2-2-1

September 27, 2025 at 07:30 AM EDT

The Line: Betting Odds: Brentford +240 / Manchester United +110 — Over/Under: 2.5

(Get latest betting odds)

In this article, we will formulate a Manchester United vs Brentford Prediction for this English Premier League Week 6 matchup on Saturday, September 27th, at the Gtech Community Stadium. Let’s take a look at the prediction for this English Premier League matchup.

Brentford Preview

Brentford has 4 points this season, with a 1-3-1 record, and are sitting on the 17th place in the Premier League standings. They have a 1-2-0 home record and a 0-1-1 away record. Brentford is coming off a 1-3 road defeat against Fulham, where they had 47% possession of the ball and 8 total shots, 3 of them on target. They had 81% completed passes, and less expected goals, with 0.60 compared to Fulham’s 1.00.

Brentford is scoring 1.20 goals per game, which ranks 13th in the Premier League, while allowing 2.00 goals per game, which is 18th. Igor Thiago is Brentford’s top scorer with 2 goals, followed by Fabio Carvalho, Kevin Schade, Dango Aboubacar Faissal Ouattara, Mikkel Damsgaard and Ethan Pinnock with 1 goal each. Jordan Henderson is Brentford’s top passer, with 1 assist.

Manchester United Preview

Manchester United has 7 points this season, with a 2-2-1 record, and are sitting on the 11th place in the Premier League standings. They have a 1-1-1 home record and a 1-1-0 away record. Manchester United is coming off a 2-1 home win against Chelsea, where they had 41% possession of the ball and 11 total shots, 4 of them on target. They had 79% completed passes, and more expected goals, with 1.84 compared to Chelsea’s 0.42.

Manchester United is scoring 1.20 goals per game, which ranks 11th in the Premier League, while allowing 1.60 goals per game, which is 14th. Bruno Fernandes is Manchester United’s top scorer with 2 goals, followed by Casemiro and Bryan Mbeumo with 1 goal each. Bryan Mbeumo is Manchester United’s top passer, with 1 assist.

Why Brentford will win


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·        Brentford has won four of its last five EPL Saturday day matches as an underdog.

·        Brentford has won each of its last three EPL Saturday day matches as an underdog.

·        Brentford has won three of its last four EPL Saturday day matches as a home underdog.

·        Brentford has won seven of its last nine EPL Saturday day home matches.

·        Manchester United has lost each of its last three EPL matches as a favorite following a league win.

·        Manchester United has lost seven of its last eight EPL matches following a league win.

·        Manchester United has lost four of its last five EPL matches as a favorite following a league win.

·        Manchester United has lost five of its last seven EPL day matches as a favorite.

·        The home team has won six of the last seven EPL matches between Brentford and Manchester United.

·        The home team has won each of Manchester United’s last three EPL matches.

Total Points Facts

·        The ‘Over 3.5 Goals’ market has hit in four of Brentford’s last five EPL home matches.

·        The ‘Over 2.5 Goals’ market has hit in four of Brentford’s last five EPL matches.

·        The ‘Over 2.5 Goals’ market has hit in each of Manchester United’s last three EPL matches.

·        The ‘Over 2.5 Goals’ market has hit in three of Brentford’s last four EPL home matches against Manchester United.

Manchester United vs Brentford Prediction

In their two meetings last season, Brentford beat Manchester United 4-3 at home, while Manchester United beat Brentford 2-1 at home. Manchester United is 3-1-1 in their last 5 meetings against Brentford. Both teams to score – Yes is 4-0 in their last 4 meetings, and over 2.5 goals is 3-1 in their last 4 meetings.

In this Manchester United vs Brentford Prediction, Manchester United is coming as +110 road favorites. Brentford has been terrible this season, with just 4 points in six games played, and have just one home win. United is 1-1 on the road, but they have been struggling on the road against Brentford. Both teams are a combined 7-0 to the over in their last 7 games, and they have 3 and 2.8 average total goals this season. Both of their meetings last season had 7 and 3 total goals, and I like the over in this matchup again.

Nikos Lagouretos's Pick: Over 2.5


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