Arsenal vs Southampton 5/25/25 Prediction English Premier League Picks

Arsenal will visit Southampton on Sunday, May 25, 2025, at the St. Mary’s Stadium in this Week 38 Premier League Matchup. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arsenal vs Southampton Prediction. We will examine:

Southampton recent form and player performance

Arsenal recent form and player performance

Recent betting trends and streaks involving Southampton

Recent betting trends and streaks involving Arsenal 

Recent betting trends in games played between the Arsenal and Southampton

A summary that ties it all together and produces a favorable betting outcome for Arsenal vs Southampton game

Southampton Preview

Southampton has only 12 points this season and is sitting on the last place of the Premier League standings, and have already been relegated. Southampton has a 2-29-6 record this season and have a terrible 1-14-3 home record. Southampton is coming off a 0-2 road defeat by Everton, and have lost 9 of their last 12 matches. Under is 4-1 in their last 5 games, as they have score just two goals in their last six matches.

Southampton is averaging just 0.68 goals per game, which is the worst in the league, while allowing 2.27 goals per game, which is also ranks last. Paul Onuachu is the top scorer for Southampton this season with 4 total goals. Mateus Fernandes is Southampton’s best passer, with 3 total assists.

Arsenal Preview

Arsenal has 71 points this season and is currently sitting on the second place of the Premier League standings. Arsenal has a 19-4-14 record this season, while having an 8-2-8 road record. They are coming off a 1-0 home victory over Newcastle, ending a five-game winless streak. Over is 6-2 in their last 8 games.

Arsenal is averaging 1.81 goals per game, which is 4th in the league, while allowing 0.89 goals per game, which is the best in the Premier League. Kai Havertz is the top scorer for Arsenal this season with 9 goals, while Leandro Trossard and Gabriel Martinelli follow with 8 goals apiece. Bukayo Saka is the team’s top passer, with 10 assists made.

Why Arsenal will win

• Arsenal has won each of its last 11 EPL matches against promoted teams.
• Southampton has lost 11 of its last 13 EPL home matches.
• Southampton has lost 16 of its last 20 EPL matches.
• Arsenal has won six of its last eight EPL matches against Southampton following a league win.

Total Points Facts

• The ‘Both Teams to Score’ market has hit in each of Arsenal’s last three EPL matches as a favorite against Southampton.
• The ‘Both Teams to Score’ market has hit in each of Southampton’s last three EPL matches as an underdog against Arsenal.
• The ‘Both Teams to Score’ market has hit in six of Arsenal’s last eight EPL matches.
• The ‘Over 2.5 Goals’ market has hit in 12 of Southampton’s last 15 EPL matches as a home underdog.
• The ‘Under 2.5 Goals’ market has hit in four of Southampton’s last five EPL matches.
• The ‘Over 2.5 Goals’ market has hit in four of Arsenal’s last five EPL matches.

Arsenal vs Southampton Prediction

In their previous meeting this season, Arsenal won 3-1 at home. Both teams are 1-1-2 in their last 4 overall meetings, and Southampton is 3-2-2 in their last 7 meetings in St. Mary’s Stadium. Under is 4-1 in their last 5 meetings in St. Mary’s Stadium.

In this Arsenal vs Southampton Prediction, Arsenal is coming as huge -340 favorites. Arsenal is rightfully favored, as they have been the superior team this season, but they have nothing to play for, as they secure a place on the top-5 places of the standings that lead to next season’s UEFA Champions League. This game is highly unpredictable, that’s why the -340 feels absurd. Southampton may as well take a draw, like they did on week 36 against Manchester City, and they have a very good history against Arsenal. Take Southampton by +1.5 goals in this one.

Nikos Lagouretos's Pick: Southampton +1.5