Aug 22, 2026; Detroit, Michigan, USA;  Detroit Lions quarterback Joshua Dobbs (6) throws passes during pregame warmups before their preseason game against the Washington Commanders at Ford Field.  Mandatory Credit: Lon Horwedel-Imagn Images
IMAGN IMAGES via Reuters Connect

Indianapolis Colts vs Detroit Lions Prediction 8/29/2026 Picks

Pick details

MATCHUP Detroit Lions Indianapolis Colts
Team Records 1-1 0-1-1
Spread +3.5 -108 -3.5 -112
Moneyline +140 -168
Total Over 35.5 (-115) Under 35.5 (-105)
Where Lucas Oil Stadium, Indianapolis, IN
When Saturday, August 29, 2026
Time 01:00 PM EDT
TV NFL Net

In this article, we will formulate a Lions vs Colts Prediction for this NFL Preseason Week 3 matchup on Saturday, August 29th. Let’s take a look at the prediction for this NFL matchup.

Indianapolis Colts Preview


The Indianapolis Colts have a 0-1-1 record in the preseason and are sitting in the 3rd place of the AFC South. They are coming off a 6-34 home defeat by the Atlanta Falcons, where they were outgained by their opponents 164-461 yards and had 45 total plays. Indianapolis had 79 passing yards, 85 rushing yards, and 10/23 completed passes, while the turnover battle was tied at 0-0. The Colts were 1/11 on third down conversions and 0/1 in the red zone.

Riley Leonard led Indianapolis with 7/14 passes and 62 passing yards. Anderson Castle had a team-high 41 rushing yards, while Chayce Owen caught 1 pass for a team-high 39 receiving yards. Defensively, Austin Ajiake led the Colts with 6 total tackles, 4 of them solo, while Cameron Ball had one sack.

Detroit Lions Preview


The Detroit Lions have a 1-1 record in the preseason and are sitting in the 1st place of the NFC North. They are coming off a 17-13 home victory over the Washington Commanders, where they outgained their opponents 279-243 yards and had 65 total plays. Detroit had 110 passing yards, 169 rushing yards, and 16/25 completed passes, while losing the turnover battle 2-1. The Lions were 9/17 on third down conversions and 1/3 in the red zone.

Luke Altmyer led Detroit with 9/13 passes and 86 passing yards. Joshua Dobbs had a team-high 53 rushing yards, while Jackson Meeks caught 4 passes for a team-high 33 receiving yards. Defensively, Chuck Clark led the Lions with 4 total tackles, 2 of them solo, while DJ Wonnum had one sack.

Lions vs Colts Prediction


The Lions have won two of their last three meetings against the Colts and have won their last two visits in Indianapolis. Over is 4-1 in their 5 meetings.

In this Lions vs Colts Prediction, the Colts are coming as -3.5 home favorites. The Lions have been playing much better in the preseason, as both their offensive and defensive line is looking better than the Colts’. The Colts are scoring less than 10 points per game and allowing 23.5, while the Lions are scoring 15.5 points per game and last time they lost in Indianapolis was back in 2008. I like the Lions as road dogs in this spot, so get the +3.5 points in this one.

Nikos Lagouretos's Pick: Detroit Lions +3.5

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