Titans vs Broncos Prediction 9/7/2025 Today’s NFL Picks

In this article we will formulate a Titans vs Broncos prediction for this NFL game on Sunday, September 7th at Mile High Stadium in Denver, Colorado. Let’s take a look at the prediction for this week 1 matchup.

Tennessee Titans Betting Preview

The Tennessee Titans went 3-14 last year and they finished last in the AFC South standings, seven games behind Houston for first place. Tennessee lost six of their first seven games last season and they failed to win back to back games at any point throughout the year. The Titans picked up wins against the Dolphins, Patriots, and Texans, while they lost to the Bears, Jets, Packers, Colts (2), Bills, Lions, Chargers, Vikings, Commanders, Jaguars (2), Bengals, and Texans. Tennessee scored 18.3 points per game last year, which was ranked 27th in the NFL, while they allowed 27.1 points against per game, which was ranked 30th. 

In the preseason, Tennessee lost their first game against the Bucs by a score of 29-7, but they did win their last two games against the Falcons and Vikings by scores of 23-20 and 23-13. Tennessee has a new quarterback this season, as Cam Ward will be leading them under center. The Titans will have Tony Pollard as their starting running back, while Ridley, Lockett, and Ayomanor will help lead the passing game. I wouldn’t say the Titans roster gives me a ton of hope, so they will need Ward to have a big rookie season. 

Denver Broncos Betting Preview

The Denver Broncos were 10-7 last season and they finished third in the AFC West standings, five games behind the Chiefs and one game behind the Chargers. Denver played very well for most of the 2024 season and they avoided losing more than two games in a row at a time, which was big for them to keep confidence. The Broncos got wins against the Bucs, Jets, Raiders (2), Saints, Panthers, Falcons, Browns, Colts, and Chiefs, while they lost to the Seahawks, Steelers, Chargers (2), Ravens, Chiefs, and Bengals. Denver made the playoffs last year, but they lost to the Bills in the first round by a score of 31-7. The Broncos scored 25.0 points per game last year, which was ranked 10th in the NFL, while they allowed 18.3 points against per game, which was ranked 3rd. 

During the preseason, Denver won all three of their games against the 49ers, Cardinals, and Saints by scores of 30-9, 27-7, and 28-19. Denver has Bo Nix back under center this season and he will look to replicate a fantastic 2024. The Broncos rushing attack will be led by JK Dobbins and RJ Harvey, while the receivers will be led by Sutton, Mims Jr, Franklin, and Engram. Denver also has one of the best defensive units in the NFL, so they should have another very solid season. 

Why the Broncos will beat the Titans 

The Broncos have won each of their last nine games as favorites.
The Titans have lost each of their last six games.
The favorites have covered the spread in each of the Broncos’ last nine games at Empower Field at Mile High.
The Titans have failed to cover the spread in 12 of their last 13 games.
The Titans have lost the first half in each of their last four games against AFC opponents.
The Broncos have won the first quarter in four of their last five Week 1 home games against AFC opponents.

Total Points Facts

Each of the Titans’ last six Sunday games as road underdogs have gone OVER the total points line.
Seven of the Broncos’ last eight games against AFC South opponents have gone UNDER the total points line.

Denver Broncos Player Prop Facts

Courtland Sutton has scored at least one touchdown in four of the Broncos’ last five Sunday regular season games.
Bo Nix has recorded 215+ passing yards in eight of the Broncos’ last nine regular season games against AFC opponents.
J.K. Dobbins has recorded 50+ rushing yards in each of his last six regular season appearances with his team as a favorite.
Evan Engram has recorded 49+ receiving yards in six of his last seven appearances with his team as a favorite.
Bo Nix has recorded 25+ completions in four of the Broncos’ last five Sunday games as favorites.
Bo Nix ranked 2nd in the league for batted pass attempts (16) last season.

Tennessee Titans Player Prop Facts 

Tony Pollard has scored at least one touchdown in three of his last four September road appearances.
Tony Pollard has recorded 62+ rushing yards in each of his last four September appearances with his team as an underdog.
Tyler Lockett has recorded 30+ receiving yards in each of his last eight September appearances with his team as a road underdog.
Tony Pollard has recorded 82+ rushing and receiving yards in each of his last six September road appearances.
Amani Hooker ranked T2nd in the AFC for interceptions (5) last season.

Matchup/League Facts

Broncos – five different players recorded 80+ receiving yards in a game last season – equal-most in the NFL.
The Broncos ranked 1st in the NFL in sacks (63.0) last season.
The Titans ranked 2nd in the NFL in yards allowed per game (311.2) last season.
The Titans ranked 2nd in the NFL in passing yards allowed per game (177.3) last season.

David Racey was 18-10 (64%) in the NFL Preseason this year. Click here for his premium plays for this week!

Titans vs Broncos Prediction 

Denver comes into this contest as a pretty heavy favorite to get the win, and with good reason, as the Titans had a miserable 2024 season. Tennessee will have Cam Ward under center, which should be a good thing in the long run, but I worry about how he will do in his first start. The Broncos have a fantastic defense and they should force a few turnovers in this game. I expect Denver to come out strong and pull away in the second half for the cover.