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Cowboys vs Panthers Prediction 10/12/2025 Today’s NFL Picks
Pick details
Dallas (2-2-1) vs Carolina (2-3)
October 12, 2025 at 01:00 PM EDT
The Line: Betting Odds: Carolina +3 — Over/Under: +49
In this article we will formulate a Cowboys vs Panthers prediction for this NFL game on Sunday, October 12th at Bank of America Stadium in Charlotte, North Carolina. Let’s take a look at the prediction for this week 6 matchup.
Prior to that win, the Cowboys tied Green Bay, lost to Chicago, beat the Giants, and lost to Philadelphia. Dallas is averaging 30.2 points per game with 272.2 passing yards and 134.4 rushing yards per game, while they are allowing 30.8 points against per game this season. Dak Prescott has completed 71.3% of his passes for 1,356 yards, 10 touchdowns, and three interceptions, while George Pickens has caught 23 passes for 357 yards and five scores. Javonte Williams has led the rushing attack with 79 carries for 447 yards and five touchdowns this year.
Prior to that win, Carolina lost to New England, beat Atlanta, lost to Arizona, and lost to Jacksonville. The Panthers are averaging 20.4 points per game with 187.0 passing yards and 128.0 rushing yards per game, while they are allowing 23.8 points against per game this season. Bryce Young has completed 60.9% of his passes for 951 yards, seven touchdowns, and four interceptions, while Tetairoa McMillan has 24 receptions for 351 yards. Rico Dowdle has led the rushing attack with 289 yards and two scores this season.
The Cowboys have lost three of their last four games as favorites following a win.
The underdogs have covered the spread in each of the Cowboys’ last six games.
The Cowboys have failed to cover the spread in five of their last six games as favorites.
The Cowboys have lost the first half in five of their last six Week 6 games.
The underdogs have won the first quarter in four the Panthers’ last five Week 6 games.
The Panthers have lost each of their last six October games against NFC opponents.
The Cowboys have covered the spread in each of their last six October games as favorites against NFC opponents.
The Panthers have failed to cover the spread in eight of their last nine Week 6 games.
The Cowboys have won the first half in each of their last four October games as favorites.
Eight of the Panthers’ last nine Sunday games at Bank of America Stadium have gone OVER the total points line.
Rico Dowdle has scored a touchdown in five of his last six home appearances against NFC East opponents.
Chuba Hubbard has recorded 49+ rushing yards in 15 of his last 17 Sunday appearances with the Panthers as underdogs.
Chuba Hubbard has recorded 69+ rushing and receiving yards in each of his last six appearances with the Panthers as underdogs.
Andy Dalton has recorded 25+ completions in three of his four previous Sunday appearances at Bank of America Stadium.
Heading into Week 6, Rico Dowdle has recorded the most rushing yards in a single game this season (206 vs Dolphins, Week 5).
George Pickens has scored at least one touchdown in each of his last five Sunday appearances.
Miles Sanders has recorded 28+ rushing yards in each of his 16 previous appearances with his team as a road favorite.
Miles Sanders has recorded 29+ rushing and receiving yards in each of his 15 previous Sunday appearances with his team as a road favorite.
Jake Ferguson has recorded 69+ receiving yards in each of his last five appearances with the Cowboys as favorites following a win.
Dak Prescott has recorded 24+ completions in each of the Cowboys’ last 11 Sunday regular season games as favorites.
Heading into Week 6, Dak Prescott ranks 2nd in the NFL in passing yards (1356) this season.
Heading into Week 6, the Panthers rank T1st in the NFL in Q4 win percentage (80.0) this season.
Cowboys – four different players have recorded 70+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
Cowboys – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
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Dallas Cowboys Betting Preview
The Dallas Cowboys are 2-2-1 this year after they defeated the Jets by a score of 37-22 last week. Dallas trailed 3-0 in the first quarter, but they scored the next 30 points to pull away for the relatively easy win. The Cowboys out gained New York by a total of 416-378, went 6-13 on third downs, and won the turnover battle by a margin of 1-0 in the game. Dak Prescott went 18-29 for 237 yards and four touchdowns, while Javonte Williams rushed 16 times for 135 yards and one score. Ryan Flournoy led the receivers with six receptions for 114 yards in the game. The Dallas defense recorded five sacks and six tackles for loss in the victory.Prior to that win, the Cowboys tied Green Bay, lost to Chicago, beat the Giants, and lost to Philadelphia. Dallas is averaging 30.2 points per game with 272.2 passing yards and 134.4 rushing yards per game, while they are allowing 30.8 points against per game this season. Dak Prescott has completed 71.3% of his passes for 1,356 yards, 10 touchdowns, and three interceptions, while George Pickens has caught 23 passes for 357 yards and five scores. Javonte Williams has led the rushing attack with 79 carries for 447 yards and five touchdowns this year.
Carolina Panthers Betting Preview
The Carolina Panthers are 2-3 this season after they defeated Miami by a score of 27-24 in their last game. Carolina trailed 17-0 late in the second quarter, but they rallied and took the lead with two minutes left for the victory. The Panthers out gained Miami by a total of 418-248, went 5-11 on third downs, and lost the turnover battle by a total of 2-0 in the game. Bryce Young went 19-30 for 198 yards, two touchdowns, and one interception, while Rico Dowdle rushed 23 times for 206 yards and one score. Tetairoa McMillan led the receivers with six receptions for 73 yards in the game. The Carolina defense recorded three sacks and nine tackles for loss in the victory.Prior to that win, Carolina lost to New England, beat Atlanta, lost to Arizona, and lost to Jacksonville. The Panthers are averaging 20.4 points per game with 187.0 passing yards and 128.0 rushing yards per game, while they are allowing 23.8 points against per game this season. Bryce Young has completed 60.9% of his passes for 951 yards, seven touchdowns, and four interceptions, while Tetairoa McMillan has 24 receptions for 351 yards. Rico Dowdle has led the rushing attack with 289 yards and two scores this season.
Why the Carolina Panthers will win
The Panthers have won each of their last three games as home underdogs.The Cowboys have lost three of their last four games as favorites following a win.
The underdogs have covered the spread in each of the Cowboys’ last six games.
The Cowboys have failed to cover the spread in five of their last six games as favorites.
The Cowboys have lost the first half in five of their last six Week 6 games.
The underdogs have won the first quarter in four the Panthers’ last five Week 6 games.
Why the Dallas Cowboys will win
The Cowboys have won each of their six previous October games against the Panthers.The Panthers have lost each of their last six October games against NFC opponents.
The Cowboys have covered the spread in each of their last six October games as favorites against NFC opponents.
The Panthers have failed to cover the spread in eight of their last nine Week 6 games.
The Cowboys have won the first half in each of their last four October games as favorites.
Total Points Facts
Ten of the Cowboys’ last 11 road games following a road win have gone UNDER the total points line.
Eight of the Panthers’ last nine Sunday games at Bank of America Stadium have gone OVER the total points line.
Carolina Panthers Player Prop Facts
Xavier Legette has recorded 28+ receiving yards in six of his last seven appearances with the Panthers as underdogs against NFC opponents.Rico Dowdle has scored a touchdown in five of his last six home appearances against NFC East opponents.
Chuba Hubbard has recorded 49+ rushing yards in 15 of his last 17 Sunday appearances with the Panthers as underdogs.
Chuba Hubbard has recorded 69+ rushing and receiving yards in each of his last six appearances with the Panthers as underdogs.
Andy Dalton has recorded 25+ completions in three of his four previous Sunday appearances at Bank of America Stadium.
Heading into Week 6, Rico Dowdle has recorded the most rushing yards in a single game this season (206 vs Dolphins, Week 5).
Dallas Cowboys Player Prop Facts
Dak Prescott has recorded 251+ passing yards in each of the Cowboys’ last six Sunday games as favorites.George Pickens has scored at least one touchdown in each of his last five Sunday appearances.
Miles Sanders has recorded 28+ rushing yards in each of his 16 previous appearances with his team as a road favorite.
Miles Sanders has recorded 29+ rushing and receiving yards in each of his 15 previous Sunday appearances with his team as a road favorite.
Jake Ferguson has recorded 69+ receiving yards in each of his last five appearances with the Cowboys as favorites following a win.
Dak Prescott has recorded 24+ completions in each of the Cowboys’ last 11 Sunday regular season games as favorites.
Heading into Week 6, Dak Prescott ranks 2nd in the NFL in passing yards (1356) this season.
Matchup/League Facts
Heading into Week 6, the Panthers rank 32nd in the NFL in Q2 points per game (2.6) this season.Heading into Week 6, the Panthers rank T1st in the NFL in Q4 win percentage (80.0) this season.
Cowboys – four different players have recorded 70+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
Cowboys – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 6.
Cowboys vs Panthers Prediction
Both of these teams have been a bit inconsistent to start this year, but they both won last weekend and will look to continue that momentum here. The Panthers play their best ball at home, as they have outscored their opponents 57-24 on their home field this year. Dallas has been very successful on offense this season, but their defense is one of the worst units in the league. I think we are going to see plenty of points in this contest and this is a great chance for Bryce Young to have a huge day in the air. Take the over here.David Racey is 31-17 (65%) in the NFL this season and he is currently #1 on the NFL Leaderboard. Click here for his premium plays for this week!
