Carolina Panthers vs Jacksonville Jaguars Prediction 9/7/2025 Today’s NFL Picks

The Carolina Panthers and the Jacksonville Jaguars meet in week 1 NFL action from EverBank Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Carolina Panthers vs. Jacksonville Jaguars prediction.

Carolina Panthers Team Preview

The Carolina Panthers enter the 2025 season determined to rebound from a 5-12 finish in 2024. Quarterback Bryce Young showed flashes of growth late last year, and the front office made major moves to support his development. The Panthers selected wide receiver Tetairoa McMillan with the eighth overall pick out of Arizona, adding a true No. 1 option to pair with Xavier Legette and veteran Adam Thielen. They also signed veteran running back Rico Dowdle to complement Chuba Hubbard in the backfield, giving Carolina a deeper, more balanced running back room. On defense, the team released Jadeveon Clowney and retooled the front line by signing Tershawn Wharton to a three-year, $54 million deal and bringing in Bobby Brown III. In the secondary, Jaycee Horn signed a four-year, $100 million extension, making him the highest-paid cornerback in the NFL. The Panthers also re-signed Mike Jackson, solidifying the outside corner positions. Edge rushers Nic Scourton and Princely Umanmielen were added through the draft, adding speed and depth to a defense that lacked bite in 2024. With upgrades across both sides of the ball, 2025 represents a huge year for the Panthers’ rebuild. If the young core gels, Carolina could take a meaningful step forward in its long-term outlook.

Why the Carolina Panthers will win

• The Jaguars have lost each of their last six games in September.
• The Panthers have won each of their last three September games as road underdogs against AFC opponents.
• The underdogs have covered the spread in eight of the Panthers’ last nine games.
• The Jaguars have failed to cover the spread in seven of their last eight September games against NFC opponents.

Carolina Panthers Player Prop Facts

• Chuba Hubbard has scored the last touchdown in four of his last five appearances with the Panthers as underdogs on the East Coast.
• Chuba Hubbard has scored at least one touchdown in five of his last six appearances with the Panthers as underdogs.
• Rico Dowdle has recorded 75+ rushing yards in each of his last five road appearances.
• Andy Dalton has recorded 243+ passing yards in eight of his last nine September road appearances against AFC opponents.
• Rico Dowdle has recorded 98+ rushing and receiving yards in each of his last five road appearances.
• David Moore has recorded 17+ receiving yards in nine of the Panthers’ last 10 games.
• Andy Dalton has recorded 23+ completions in six of his last eight Week 1 road appearances.
• Mike Jackson ranked T1st in the NFC for passes defensed (17) last season.

Jacksonville Jaguars Recap

After a brutal 4-13 season in 2024 snapped a two-year playoff streak, the Jacksonville Jaguars enter 2025 with a new regime and retooled roster. Former Rams assistant Liam Coen takes over as head coach, and new GM James Gladstone has orchestrated major offseason moves. The team traded away top receiver Christian Kirk and veteran left tackle Cam Robinson, and released tight end Evan Engram. To help Trevor Lawrence bounce back after missing seven games with injuries last year, the Jaguars added receiver Dyami Brown to a receiving corps now led by emerging second-year wideout Brian Thomas Jr. and veteran Gabe Davis, while running back Travis Etienne Jr. continues to spearhead the backfield. They also fortified the offensive line by signing guard Patrick Mekari and center Robert Hainsey to join tackles Walker Little and Anton Harrison, while second-year tight end Brenton Strange replaces Engram as the starter. On defense, new coordinator Anthony Campanile will lean on edge rushers Josh Allen and Travon Walker and tackling machine Foyesade Oluokun. Jacksonville solidified the defensive front with former 49ers standout Arik Armstead and addressed a secondary that ranked last in pass defense by signing cornerback Jourdan Lewis and safety Eric Murray to complement standout corner Tyson Campbell. The Jaguars also drafted two-way phenom Travis Hunter with the No. 2 overall pick, planning to use him at wide receiver and cornerback. With all these changes, Jacksonville aims to contend for the AFC South title again in 2025.

Why the Jacksonville Jaguars will win

• The Panthers have lost each of their last nine games in Florida.
• The home team has won five of the last six games between the Panthers and Jaguars.
• The Panthers have failed to cover the spread in eight of their last nine games in Florida.
• The favorites have covered the spread in seven of the Panthers’ last eight Week 1 games.

Jacksonville Jaguars Player Prop Facts

• Brian Thomas has scored at least one touchdown in five of the Jaguars’ last six games at EverBank Stadium.
• Trevor Lawrence has recorded 24+ completions in three of the Jaguars’ last four September games as favorites.
• Travis Etienne has recorded 15+ receiving yards in each of the Jaguars’ last five games.
• Travis Etienne has recorded 44+ rushing yards in seven of his last eight appearances in Florida.
• Tank Bigsby has recorded 33+ rushing and receiving yards in each of the Jaguars’ last six games.
• Travis Etienne ranked 1st in the league amongst qualified players for broken tackle percentage (50.0%) last season.

Total Points Facts

• Each of the Panthers’ last seven games played on the East Coast have gone OVER the total points line.
• Seven of the Jaguars’ last eight games against NFC South opponents have gone UNDER the total points line.
• Three of the last four Sunday games at EverBank Stadium have gone UNDER the total points line.

Carolina Panthers vs. Jacksonville Jaguars Prediction

I’m on the Jaguars here. I just am not understanding all this love for Carolina for the upcoming season. The Panthers had moments where they looked solid, but who didn’t, and the cons far outweighed the pros for the Panthers in my opinion. Jacksonville had a tough year themselves, but keep in mind this is also a Jaguars team that’s seen playoff action before for the most part and watching the preseason, even though it’s preseason, I liked the edge this team had with Liam Coen leading the charge and the swagger if you will that the Jags had. I think this is going to be a Jaguars team to keep an eye on in 2025, and it starts here. Give me Jacksonville.