Sep 28, 2025; Tampa, Florida, USA; Tampa Bay Buccaneers quarterback Baker Mayfield (6) throws the ball during the second half against the Philadelphia Eagles at Raymond James Stadium. Mandatory Credit: Kim Klement Neitzel-Imagn Images

Buccaneers vs Seahawks Prediction 10/5/2025 Today’s NFL Picks

Pick details

Tampa Bay (3-1) vs Seattle (3-1)

October 5, 2025 at 04:05 PM EDT

The Line: Betting Odds: Seattle -3.5 — Over/Under: +44.5

(Get latest betting odds)

In this article we will formulate a Buccaneers vs Seahawks prediction for this NFL game on Sunday, October 5th at Lumen Field in Seattle, Washington. Let’s take a look at the prediction for this week 5 matchup.

Tampa Bay Buccaneers Betting Preview

The Tampa Bay Buccaneers are 3-1 this year after they lost to Philadelphia by a score of 31-25 last week. Tampa Bay trailed 24-3 in the second quarter, but they cut the deficit to 31-23 with about 12 minutes left, before coming up short in the comeback attempt. The Buccaneers out gained the Eagles by a total of 376-200, went 3-13 on third downs, and lost the turnover battle by a margin of 2-0 in the game. Baker Mayfield went 22-40 for 289 yards, two touchdowns, and one interception, while Bucky Irving rushed 15 times for 63 yards. Irving also led the TB receivers with five receptions for 102 yards and one score in the loss. The Bucs defense recorded two sacks and 11 tackles for loss in the game. 

In their first three games, Tampa Bay defeated the Falcons by a score of 23-20, the Texans by a score of 20-19, and the Jets by a score of 29-27. The Buccaneers are averaging 24.3 points per game with 211.8 passing yards and 124.0 rushing yards per game, while they are allowing 24.3 points against per game this season. Baker Mayfield has completed 59.7% of his passes for 904 yards, eight touchdowns, and one interception, while Emeka Egbuka has caught 18 passes for 282 yards and four scores. Bucky Irving has led the ground game with 237 yards on 71 carries this year. 

Seattle Seahawks Betting Preview

The Seattle Seahawks are 3-1 this season after they defeated Arizona by a score of 23-20 in their last game. Seattle trailed 3-0 in the first quarter, but they scored the next 17 points to pull away, before needing a last second field goal for the win. The Seahawks out gained Arizona by a total of 384-253, went 6-13 on third downs, and won the turnover battle by a margin of 2-1 in the game. Sam Darnold went 18-26 for 242 yards and one touchdown, while Kenneth Walker III carried the ball 19 times for 81 yards. Jaxon Smith-Njigba led the Seattle receivers with four receptions for 79 yards in the win. The Seahawks defense recorded six sacks and five tackles for loss in the game. 

In their first three games, Seattle lost to San Francisco, but did beat Pittsburgh by a score of 31-17 and New Orleans by a score of 44-13. The Seahawks are averaging 27.8 points per game with 221.5 passing yards and 110.8 rushing yards per game, while they are allowing 16.8 points against per game this season. Sam Darnold has completed 70% of his passes for 905 yards, five touchdowns, and two interceptions, while Jaxon Smith-Njigba has caught 26 passes for 402 yards and one score. Kenneth Walker III has led the rushing attack with 58 carries for 244 yards and three scores this season. 

Why the Buccaneers will beat the Seahawks 

The Buccaneers have won each of their last two games as road underdogs.
The Seahawks have lost four of their last six games as favorites following a Division game.
The road team has covered the spread in each of the Buccaneers’ last six games.
The Seahawks have failed to cover the spread in seven of their last eight games as favorites following a Division game.
The Seahawks have lost the first quarter in three of their last four home games.
The Seahawks have lost the first half in six of their last seven games at Lumen Field against teams that held a winning record.

Total Points Facts

Each of the Seahawks’ last four home games against NFC South opponents have gone OVER the total points line.
Each of the Buccaneers’ last four October games against NFC West opponents have gone OVER the total points line.

Seattle Seahawks Player Prop Facts


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Cooper Kupp has recorded 43+ receiving yards in each of his last nine October appearances with his team as a favorite against NFC opponents.
Cooper Kupp has recorded 59+ rushing and receiving yards in each of his last nine October appearances with his team as a favorite against NFC opponents.
AJ Barner has scored a touchdown in each of the Seahawks’ last four games against teams with a winning record.
Zach Charbonnet has recorded 47+ rushing yards in each of his last four appearances following a road win.
Sam Darnold has recorded 231+ passing yards in 12 of his last 13 regular season appearances with his team as a favorite.
Sam Darnold has recorded 21+ completions in five of his last six appearances with his team as a home favorite against NFC opponents.
Heading into Week 5, Jason Myers ranks T1st in the NFC for made field goals (9) this season.

Tampa Bay Buccaneers Player Prop Facts

Rachaad White has scored a touchdown in four of the Buccaneers’ last five road games against teams with a winning record.
Rachaad White has scored the last touchdown in each of the Buccaneers’ last three Sunday games played on the West Coast.
Rachaad White has recorded 10+ receiving yards in each of the Buccaneers’ last eight games as moderate underdogs (+3.5 to +7.0 points).
Rachaad White has recorded 32+ rushing and receiving yards in 25 of his last 26 appearances following a loss.
Rachaad White has recorded 18+ rushing yards in each of the Buccaneers’ last 13 regular season games as road underdogs.
Heading into Week 5, Chase McLaughlin ranks T1st in the NFL in 50+ yard field goals made (4) this season.

Matchup/League Facts

Heading into Week 5, the Seahawks rank 1st in the NFL in Q3 opponent points per game (0.8) this season.
Heading into Week 5, the Seahawks rank T1st in the NFL in Q1 win percentage (75.0) this season.
Heading into Week 5, the Buccaneers rank T1st in the NFL in Q3 win percentage (75.0) this season.
Heading into Week 5, the Buccaneers rank 1st in the NFL in average point differential in third quarters this season (+3.5).

Buccaneers vs Seahawks Prediction 

Both of these teams come into this matchup with a 3-1 record to start the season, so this is a big game in the NFC. Tampa Bay has had some issues defensively, but their offense has been very good, especially in the air. Seattle nearly allowed Arizona to make a crazy comeback last week and I think they are going to struggle to stop Baker and the TB passing attack. Seattle should be able to move the ball throughout the game, but I like Tampa Bay with the points here. 

David Racey is 15-3 (83%) in the NFL over the last two weeks and he has been red hot this season. Click here for his premium plays for this week!

David Racey's Pick: Buccaneers +3.5

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