LA Rams vs San Francisco 49ers Prediction NFL Picks 12/12/24

Pick details

San Francisco 49ers (6-7) vs LA Rams (7-6)

December 12, 2024 at 08:15 PM EST

The Line: Betting Odds: San Francisco 49ers -2.5 / LA Rams +2.5 — Over/Under: 47.5

(Get latest betting odds)

The Los Angeles Rams and San Francisco 49ers meet Thursday in week 15 NFL action at Levi’s Stadium. Here’s an LA Rams vs San Francisco 49ers Prediction. This article will include an LA Rams vs San Francisco 49ers Pick.

Los Angeles Rams Betting Preview

The Los Angeles Rams beat the Saints and Bills, and they play the Jets next. The Rams have won 3 straight road games. Matthew Stafford is completing 66.7 percent of his passes for 3,303 yards, 19 touchdowns, and 7 interceptions. Puka Nacua and Cooper Kupp have combined for 1,365 receiving yards and 9 touchdowns, while Tutu Atwell has 35 receptions.

The Los Angeles Rams ground game is averaging 103 yards per contest, and Kyren Williams leads the way with 1,013 yards and 12 touchdowns. Defensively, Los Angeles is allowing 25.5 points and 366.1 yards per game. Christian Rozeboom leads the Los Angeles Rams with 111 tackles, Byron Young has 6 sacks and Jaylen McCollough has 4 interceptions.

San Francisco 49ers Betting Preview

The San Francisco 49ers lost to the Bills, beat the Bears, and play the Dolphins next. The San Francisco 49ers have split their last 6 home games. Brock Purdy is completing 66.8 percent of his passes for 3,032 yards, 15 touchdowns, and 8 interceptions. George Kittle and Jauan Jennings have combined for 1,574 receiving yards and 14 touchdowns, while Deebo Samuel Sr. has 40 receptions.

The San Francisco 49ers ground game is averaging 138.9 yards per contest, and Jordan Mason leads the way with 789 yards and 3 touchdowns. Defensively, San Francisco is allowing 23.7 points and 298.5 yards per game. Fred Warner leads the San Francisco 49ers with 91 tackles, Leonard Floyd has 8.5 sacks and Deommodore Lenoir has 2 interceptions.

Why the Los Angeles Rams will win

  • The 49ers have lost five of their last six games as home favorites following a win.
  • The Rams have won each of their last five games in December.
  • The 49ers have failed to cover the spread in each of their last nine games as favorites following a win.
  • The Rams have covered the spread in seven of their last eight games in December.
  • The Rams have won the first half in each of their last three December games as underdogs.

San Francisco 49ers Player Prop Facts

  • Deebo Samuel has scored at least one touchdown in each of his four previous December appearances with the 49ers as favorites against NFC West opponents.
  • Brock Purdy has recorded 33+ rushing yards in four of the 49ers’ last five home games against NFC opponents.
  • George Kittle has recorded 57+ receiving yards in each of his last six appearances with the 49ers as favorites.
  • Brock Purdy has recorded 255+ passing yards in each of the 49ers’ last three December home games.
  • Brock Purdy has thrown two or more touchdowns in each of the 49ers’ last eight December games as favorites against NFC opponents.
  • Deebo Samuel has recorded 94+ rushing and receiving yards in each of his last four Thursday appearances.
  • Heading into Week 15, Fred Warner ranks T2nd in the league for forced fumbles (4) this season.

Los Angeles Rams Player Prop Facts

  • Kyren Williams has scored the first touchdown in each of the Rams’ last three December games.
  • Matthew Stafford has recorded 23+ completions in 10 of his last 11 Thursday appearances.
  • Matthew Stafford has recorded 254+ passing yards in each of his last eight December appearances with his team as a road underdog against NFC opponents.
  • Kyren Williams has recorded 97+ rushing and receiving yards in each of the Rams’ last seven December games.
  • Kyren Williams has recorded 87+ rushing yards in each of the Rams’ last four December games against NFC opponents.
  • Matthew Stafford has thrown two or more touchdowns in each of the Rams’ last four games against NFC opponents.
  • Kyren Williams has scored at least one touchdown in each of the Rams’ last seven games as underdogs against NFC opponents.
  • Colby Parkinson has recorded 10+ receiving yards in each of the Rams’ last seven games as underdogs against NFC opponents.
  • Heading into Week 15, Kamren Kinchens has recorded the equal-most interceptions in a single game this season (2 vs Seahawks, Week 9).

Matchup/League Facts

  • Last season, the 49ers were NFC Champions for the first time since the 2019 season.
  • Heading into Week 15, the 49ers rank 3rd in the NFL in yards allowed per game (298.5) this season.
  • Heading into Week 15, the Rams rank 30th in the NFL in Q1 points per game (2.1) this season.
  • Heading into Week 15, the Rams rank T29th in the NFL in Q1 opponent points per game (5.8) this season.

LA Rams vs San Francisco 49ers Prediction

The San Francisco 49ers are going to get the benefit of the doubt at home on a short week, but they haven’t looked great this season and aren’t a team I’m excited to be back in the favorite role. The Los Angeles Rams are as healthy as they’ve been in a while, and they’ve won 3 of their last 4 games, which includes a massive win over the Bills. The Rams have won the last two games against the 49ers. The Rams are 6-4 ATS in their last 10 games as an underdog, and 4 of those covers were outright wins. You can argue the Rams are playing the better ball right now. Give me the points in a game the Rams could win outright. 

Randy Chambers's Pick: LA Rams +2.5

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