Arizona Cardinals vs Buffalo Bills Prediction NFL Picks 9/8/24

-Recent Betting trends and streaks involving Arizona

-Recent Betting trends and streaks involving Buffalo

-Recent betting trends in games played between Arizona and Buffalo.

-A summary that ties it all together and produces a favorable betting outcome for Today’s Game between the Cardinals and Bills. 

Can the Cardinals surprise some teams?

The Cardinals seem to be a team that is forgotten about right now, but don’t let that fool you, this is a team that is talented and if a few things fall into place, this could be a strong season for Arizona. Murray is healthy, or as healthy as he can be because he always seems to be a risk of getting injured again. He has some big-time weapons too and that includes Marvin Harrison Jr who was taken with the 4th overall pick. Harrison could be a generational talent and they should look his way plenty. Running back James Connor is the starter but Trey Benson is someone who could be first on the depth chart by the end of the year. 

The Cardinals' defense is still a major question mark, but they are also more talented. Darius Robinson was taken with the second first-round pick, and he should be a big upgrade for a defensive front that wasn’t great last year. The Cards will meet the Rams after this one.

Bills Look Different This Season

The Bills were supposed to be one of the top offenses in football last year, but they were inconsistent and some changes were made. Stefon Diggs was traded out, and they also let Gabe Davis go. To replace the two guys they brought in Curtis Samuel and also drafted Keon Coleman. This offense still starts and ends with Josh Allen and they are going to need him to have a huge year. The offensive line for the Bills should also be good, and I would expect them to run plenty in this game. 

If it wasn’t for injuries last year the Bills defense would have been one of the better in the league, but injuries hit and that led to some production failure. Matt Milano got hurt and missed most of the season but he is back and healthy. Terrel Bernard also stepped up in his absence and will play a big role on this year's team. Cole Bishop is only in his second year but he will be one of the starting safeties. They are going to need him to be solid here to really sure up the backend of the defense. The Bills will face the Dolphins following this game.

Why the Bills Will Beat the Cardinals

• The Bills have won 10 of their last 11 home games against NFC opponents on a winning streak.
• The Cardinals have lost seven of their last eight games against AFC opponents on a winning streak.
• The Bills have covered the spread in 10 of their last 11 September games against NFC opponents.
• The Cardinals have failed to cover the spread in each of their last four games against AFC East opponents.
• The Bills have won the first quarter in eight of their last nine games against NFC West opponents.
• The Bills have scored the first touchdown in 11 of their last 12 home games against NFC opponents.
• The Bills have won the first half in each of their last eight September games as home favorites.

Arizona Cardinals vs Buffalo Bills Prediction

I do think the Cardinals are going to be better this season, but that isn’t going to exactly start in this game. Even without Diggs, this Bills offense is going to have no issue here. Allen is going to get back to his MVP form, and Kyler Murray is going to have a solid game, but the Arizona defense might not even force a punt. The Bills offensive show is going to be the difference here as they will get the job done. Back the Bills against the spread here.