Oct 22, 2025; Dallas, Texas, USA;   San Antonio Spurs guard Stephon Castle (5) dunks against the Dallas Mavericks during the second half at American Airlines Center. Mandatory Credit: Kevin Jairaj-Imagn Images
Kevin Jairaj-Imagn Images

San Antonio Spurs vs New Orleans Pelicans Prediction 10/25/2025 Today’s NBA Picks

Pick details

San Antonio (1-0) vs New Orleans (0-1)

October 24, 2025 at 08:00 PM EDT

The Line: Betting Odds: New Orleans +3.5 — Over/Under: +231.5

(Get latest betting odds)

The San Antonio Spurs and the New Orleans Pelicans duke it out at the Smoothie King Center on Friday night.

San Antonio Spurs Betting Preview 

The San Antonio Spurs will be aiming for a second straight victory after smashing the Mavericks in a dominant 125-92 road win on Wednesday night. Victor Wembenyama led the team with 40 points, 15 rebounds and three blocks on 15 of 21 shooting, Stephon Castle added 22 points with seven rebounds and six assists while Dylan Harper chipped in with 15 points off the bench. As a team, the Spurs shot a sizzling 57 percent from the field and eight of 20 from the 3-point line as they leaned heavily on Wembenyama who put on a show and barely missed a shot as he filled up the stat sheet in just 30 minutes of action. On the defensive end, the Spurs did a great job of limiting the Mavericks to just 37 percent shooting from the field and they were relentless in the second half where they allowed just 41 points. 

New Orleans Pelicans Betting Preview 

Meanwhile, the New Orleans Pelicans will be looking to rebound in this matchup after getting beaten by the shorthanded Grizzlies in a 128-122 road defeat on Wednesday. Zion Williamson looked fantastic in his first outing as he led the team with 27 points, nine rebounds, five assists and five steals on 10 of 21 shooting, Herbert Jones, Jordan Poole and Jeremiah Fears each scored 17 points while Trey Murphy and Saddiq Bey scored 13 points apiece. As a team, the Pelicans shot 45 percent from the field and 10 of 27 from the 3-point line as they looked to be in control after they poured in 67 points in the first half to lead by 15 points at one stage, but they couldn’t hold onto their lead in the third quarter where they got outscored by an incredible 41-22 as they had no answer for the Grizzlies’ due of Ja Morant and Jaren Jackson Jr. 

San Antonio v New Orleans Free Prediction

The Spurs are still missing some key players with De’Aaron Fox, Jeremy Sochan and Kelly Olynyk all ruled out, while the Pelicans have ruled out Dejounte Murray and they are keeping eyes on Karlo Matkovic and Yves Missi who are both questionable. These two squads split four meetings last season with three of those games being decided by six points or less so we could be in for another close contest. The Pelicans might be tempting as the slight underdogs at home, but I can’t go past these Spurs after what I saw from Wembenyama in their season opener. The Pelicans are an improvement from what they showed us last season, but I am sticking with the Spurs to take care of business on the road in this one.

Peter Tran's Pick: San Antonio -3.5

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