Feb 20, 2025; Indianapolis, Indiana, USA; Memphis Grizzlies center Zach Edey (14) holds  the ball while Indiana Pacers center Myles Turner (33)  defends in the second half at Gainbridge Fieldhouse. Mandatory Credit: Trevor Ruszkowski-Imagn Images
Trevor Ruszkowski-Imagn Images

Indiana Pacers vs Memphis Grizzlies Prediction 10/25/2025 Today’s NBA Picks

Pick details

Indiana (0-1) vs Memphis (1-1)

October 25, 2025 at 08:00 PM EDT

The Line: Betting Odds: Memphis +1 — Over/Under: +237.5

(Get latest betting odds)

The Indiana Pacers and Memphis Grizzlies meet Saturday in NBA action at the FedExForum. Here’s a Indiana Pacers vs Memphis Grizzlies Prediction. This article will include a Indiana Pacers vs Memphis Grizzlies Pick.

Indiana Pacers Betting Preview

The Indiana Pacers lost to the Thunder, and they play the Timberwolves and Mavericks next. The Pacers hope to avoid their first 0-2 start since the 2022-23 season.


The Indiana Pacers are averaging 135 points on 43.8 percent shooting and allowing 141 points on 45.3 percent shooting. Bennedict Mathurin is averaging 36 points and 11 rebounds, while Pascal Siakam is averaging 32 points and 15 rebounds. Obi Toppin is the third double-digit scorer, and Ben Sheppard is grabbing 8 rebounds. The Indiana Pacers are shooting 30.2 percent from beyond the arc and 75 percent from the free-throw line. The Indiana Pacers are allowing 8.6 percent shooting from deep and are grabbing 55 rebounds per game.

Memphis Grizzlies Betting Preview


The Memphis Grizzlies beat the Pelicans, lost to the Heat, and they play the Warriors next. The Grizzlies have won 5 of their last 8 regular season games.

The Memphis Grizzlies are averaging 121 points on 45.1 percent shooting and allowing 134 points on 50 percent shooting. Ja Morant is averaging 23.5 points and 2.5 rebounds, while Jaren Jackson Jr. is averaging 18.5 points and 1 assist. Cedric Coward is the third double-digit scorer, and Jaylen Wells is grabbing 3.5 rebounds. The Memphis Grizzlies are shooting 29.3 percent from beyond the arc and 84.5 percent from the free-throw line. The Memphis Grizzlies are allowing 43.3 percent shooting from deep and are grabbing 40 rebounds per game.

Why the Memphis Grizzlies will win

  • The Grizzlies have won 14 of their last 16 games against Eastern Conference opponents that held a losing record.
  • The Pacers have lost each of their last four games at FedExForum.
  • The Pacers have failed to cover the spread in eight of their last nine games on the first leg of a back-to-back.
  • The Grizzlies have covered the spread in seven of their last eight home games against Central Division opponents following a loss.

Why the Indiana Pacers will win

  • The Pacers have won each of their last six games after coming off overtime.
  • The Grizzlies have lost 17 of their last 18 games as underdogs.
  • The Grizzlies have failed to cover the spread in nine of their last 10 games when playing with a rest disadvantage.
  • The Pacers have covered the spread in seven of their last eight games against opponents who are on the second leg of a back-to-back.

Total Points Facts

  • Seven of the Grizzlies’ last eight games at FedExForum have gone OVER the total points line.
  • Each of the Pacers’ last five road games on the first leg of a back-to-back have gone UNDER the total points line.

Indiana Pacers Player Facts

  • Bennedict Mathurin ranks 2nd amongst qualified players for fast break points per game (9.0) this season.
  • Aaron Nesmith ranks T8th amongst qualified Guards for rebounds per game (7.0) this season.

Matchup/League Facts

  • The Grizzlies rank 1st in the league for H2 points per game this season (69.5).
  • The Grizzlies rank 30th in the league for H1 opponent points per game this season (76.5).
  • The Pacers rank 30th in the league for opponent rebounds per game this season (60.0).
  • The Pacers rank T1st in the league for opponent blocks per game this season (2.0).

Indiana Pacers vs Memphis Grizzlies Injury Report


The Grizzlies will be without Vince Williams Jr., Ty Jerome, Scotty Pippen Jr., Brandon Clarke, and Zach Edey. Kentavious Caldwell-Pope and Ja Morant are questionable.

The Pacers will be without Tyrese Haliburton, Andrew Nembhard, T.J. McConnell, Kam Jones, and Quenton Jackson. Johnny Furphy is questionable with a foot injury.

Indiana Pacers vs Memphis Grizzlies Prediction


There are a lot of banged up bodies on both teams, so nothing would surprise me in this matchup. However, despite being on the end of a back-to-back, if the Grizzlies aren’t eager to rebound from that effort last night against the Heat, something is wrong. The Heat set a franchise scoring record in the first half and scored 146 points total. It was embarrassing. The Pacers are down 3 key rotation guys in Haliburton, TJ, and Nembhard. This is a gut check game for the Grizzlies. Lose this, and I’m reaching for a red flag early. Give me the Grizzlies.

Randy Chambers's Pick: Memphis Grizzlies +1

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