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Detroit Pistons vs San Antonio Spurs Prediction 2/21/25 NBA Picks

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San Antonio Spurs (24-29) vs Detroit Pistons (29-26)

February 21, 2025 at 08:30 PM EST

The Line: Betting Odds: San Antonio Spurs +4.5 — Over/Under: 232.5

(Get latest betting odds)

The Detroit Pistons and San Antonio Spurs meet Friday in NBA action at the Moody Center. Here’s a Detroit Pistons vs San Antonio Spurs Prediction. This article will include a Detroit Pistons vs San Antonio Spurs Pick.

Detroit Pistons Betting Preview 

The Detroit Pistons beat the Bulls and Hornets, and they play the Hawks, Clippers, and Celtics next. The Detroit Pistons are averaging 114.6 points on 47 percent shooting and allowing 113.1 points on 46.4 percent shooting. Cade Cunningham is averaging 25.4 points and 6.3 rebounds, while Malik Beasley is averaging 16.5 points and 1.7 assists. Tobias Harris is the third double-digit scorer and Jalen Duren is grabbing 10.2 rebounds. The Detroit Pistons are shooting 36 percent from beyond the arc and 78.4 percent from the free-throw line. The Detroit Pistons are allowing 37 percent shooting from deep and are grabbing 45.3 rebounds per game.

San Antonio Spurs Betting Preview 

The San Antonio Spurs lost to the Celtics, beat the Suns, and then play the Pelicans, Rockets, and Grizzlies next. The San Antonio Spurs are averaging 113.2 points on 46.2 percent shooting and allowing 114.4 points on 46.4 percent shooting. De’Aaron Fox is averaging 21.6 points and 3.4 rebounds, while Devin Vassell is averaging 15.9 points and 2.9 assists. Stephon Castle is the third double-digit scorer and Harrison Barnes is dishing 1.8 assists. The San Antonio Spurs are shooting 35.2 percent from beyond the arc and 78.8 percent from the free-throw line. The San Antonio Spurs are allowing 35.9 percent shooting from deep and are grabbing 45.1 rebounds per game.

Detroit Pistons vs San Antonio Spurs Injury Report

The San Antonio Spurs will be without Riley Minix and Charles Bassey. Victor Wembanyama is out for the season due to a blood clot.

The Detroit Pistons will continue to be without Jaden Ivey due to a broken leg. 

Detroit Pistons vs San Antonio Spurs Prediction

I get the Spurs got bad news on Wembanyama and are on the end of a back-to-back. I still don’t understand this line. The Pistons have struggled with consistency and wins over the Bulls and Hornets don’t move the needle. Also, I like that the Spurs have had a chance to get back in the swing of things, while the Pistons still haven’t played in a week. The Spurs still have good players on their team and don’t have to travel after playing last night. I believe this line is a bit of an overreaction to the Wemby news, as I’m just not here with the Pistons to lay this sort of number on the road. Give me the Spurs in a game they could win outright.

Randy Chambers's Pick: San Antonio Spurs +4.5

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